Intracranial vascular complications in AIDS


  • Yuris L. Dzenis Pauls Stradins Clinical University Hospital, Riga, Latvia
  • Zanda Yu. Arajuma Latvian University, Riga, Latvia
  • Elina E. Liepina Latvian University, Riga, Latvia
  • Eva I. Voita Latvian University, Riga, Latvia



HIV, AIDS, antiretroviral therapy, HIV-associated cerebral vasculopathy, fusiform aneurysm, stenosis, occlusion, stroke


The article analyzed intracranial pathomorphological changes in HIV patients as well as describes vessel wall changes leading to ischemic or hemorrhagic stroke. There are considered etiological factors for ischemic and hemorrhagic stroke in HIV patients. The article describes varied pathological processes and morphological changes in brain vessels which are called HIV-associated cerebral vasculopathy. Radiologically HIV-associated cerebral vasculopathy is characterized by fusiform aneurysms, dolichoectasia, artery stenosis or occlusion. Stroke clinical manifestation is the same for patients with HIV as for the other population, although the average age in HIV patients is much younger. The principles for stroke therapy are the same in HIV patients as in general population. Drug and surgical treatment strategies are both used. The most common surgical method is endovascular technique. Anti-stroke therapy is recommended to be completed with antiretroviral therapy being continued.

Author Biographies

Yuris L. Dzenis, Pauls Stradins Clinical University Hospital, Riga

Neurosurgical Clinic

Zanda Yu. Arajuma, Latvian University, Riga

Medical Faculty

Elina E. Liepina, Latvian University, Riga

Medical Faculty

Eva I. Voita, Latvian University, Riga

Medical Faculty


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How to Cite

Dzenis, Y. L., Arajuma, Z. Y., Liepina, E. E., & Voita, E. I. (2018). Intracranial vascular complications in AIDS. Ukrainian Neurosurgical Journal, (2), 5–11.



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