Modern approaches to cryopreservation of mesenchymal stem cells




mesenchymal stem cells, multipotent cells, cryopreservation, cryoprotectants, dimethyl sulfoxide


The problem of treating inflammatory and degenerative lesions of the central nervous system remains relevant. In recent years, advances in the treatment of diseases are associated with the development of cellular technology. The umbilical cord stem cells exhibit the most promise for use in clinical practice. Its recovery does not raise any moral and ethical conflicts, and the culturing process is quite simple. The prospect of clinical application of human umbilical cord mesenchymal stem cells raises a question of choosing the optimal method for long-term storage (cryopreservation) considering freezing mode, type of cryoprotectants and storage time. This review focuses on the analysis of recent papers about cryopreservation of mesenchymal stem cells, including umbilical cord stem cells.

Author Biographies

Olga O. Maslova, Institute of Genetic and Regenerative Medicine of NAMS of Ukraine

Department of Gene Technology

Olena G. Deriabina, Institute of Genetic and Regenerative Medicine of NAMS of Ukraine

Department of Gene Technology

Leonid D. Pichkur, Romodanov Neurosurgery Institute

Restorative Neurosurgery Department

Svetlana A. Verbovska, Romodanov Neurosurgery Institute

Restorative Neurosurgery Department

Samuel T. Akinola, Romodanov Neurosurgery Institute

Restorative Neurosurgery Department


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How to Cite

Maslova, O. O., Deriabina, O. G., Pichkur, L. D., Verbovska, S. A., & Akinola, S. T. (2017). Modern approaches to cryopreservation of mesenchymal stem cells. Ukrainian Neurosurgical Journal, (1), 5–10.



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