Ultrastructural changes of optic analyzer elements after intracranial part of optic nerve traumatic injury in experiment
Keywords:optic nerve, model of optic nerve injury, electronic microscopy
AbstractExperimental research data about rabbit’s optic nerve ultrastructure on different levels in remote period after left optic nerve cutting are generalized. In remote periods of research in all links of optic analyzer destructive-degenerative and reactive-reparative changes were observed. Disorders of neurons’ synaptic apparatus did not disappear in remote period, and showed themselves as plastic rebuilding, and their morphological criteria, in particular — perforated contact areas presence.
Шеремет Н. Л. Травматическая оптическая нейропатия / Н.Л. Шеремет, О.К. Воробьева // Материалы X науч.-практ. нейроофтальмол. конф. «Актуальные вопросы нейроофтальмологии». — М., 2008. — С.31–35.
Lyon M.J. Tests of the regenerative capacity of tectal efferent axons in the frog, Rana pipiens / M.J. Lyon, D.J. Stelzner // J. Comp. Neurol. — 1987. — V.255. — Р.511–525.
Thanos S. Mechanisms governing neuronal degeneration and axonal regeneration in the mature retinofugal system / S. Thanos, H. Thiel // J. Cell. Sci. — 1991. — V.15. — Р.125–134.
Cajal S.R. Traumatic degeneration and regeneration of the optic nerve and retina / S.R. Cajal // Degeneration and regeneration of the nervous system; ed. R. May. — N.Y.: Hafner, 1928. — V.2. — P.583–596.
Richardson P.M. Regeneration and retrograde degeneration of axons in the rat optic nerve / P.M. Richardson, V.M. Issa, S. Shemie // J. Neurocytol. — 1982. — V.11. — Р.949–966.
Persistent and injury-induced neurogenesis in the vertebrate retina / P. Hitchcock, M. Ochocinska, A. Sieh [et al.] // Prog. Retin. Eye Res. — 2004. — V.23, N2. — P.183–194.
Amato M.A. Retinal stem cells in vertebrates: parallels and divergences / M.A. Amato, E. Arnault, M. Perron // Int. J. Dev. Biol. — 2004. — V.48, N8–9. — P.993–1001.
Гайер Г. Электронная гистохимия: пер.с нем.; под. ред. Н. Г. Райхлина/ Г. Гайер. — М.: Мир, 1974. — 488 с.
Reynolds E.S. The use of lead citrate at high pH as an electronopague stain in electron microscopy / E.S. Reynolds // J. Cell. Biol. — 1963. — V.17. — P.208–212.
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Copyright (c) 2010 V. I. Tsymbaliuk, A. T. Nosov, Yu. V. Tsymbaliuk, V. V. Vaslovich, V. V. Medvedev
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