Diagnosis аnd neurosurgical treatment of Cushing’s disease

Authors

  • Aleksandr Guk Romodanov Neurosurgery Institute, Kiev, Ukraine
  • Oleksandr Voznyak Romodanov Neurosurgery Institute, Kiev, Ukraine
  • Nikolay Guk Romodanov Neurosurgery Institute, Kiev, Ukraine
  • Vyacheslav Pazyuk Romodanov Neurosurgery Institute, Kiev, Ukraine
  • Olga Chuvashova Romodanov Neurosurgery Institute, Kiev, Ukraine
  • Elena Salnikova Romodanov Neurosurgery Institute, Kiev, Ukraine
  • Vitaliy Zakordonets Romodanov Neurosurgery Institute, Kiev, Ukraine
  • Oksana Zemskova Romodanov Neurosurgery Institute, Kiev, Ukraine
  • Kristiana Robak Romodanov Neurosurgery Institute, Kiev, Ukraine
  • Sergiy Makeyev Romodanov Neurosurgery Institute, Kiev, Ukraine
  • Olena Danevych Romodanov Neurosurgery Institute, Kiev, Ukraine

DOI:

https://doi.org/10.25305/unj.57788

Keywords:

Cushing’s disease, pituitary adenoma, adrenocorticotropic hormone, cortisol, Nelson’s syndrome, transsphenoidal approach

Abstract

The informing of existing diagnostic methods was determined. The optimal algorithm for Cushing’s disease diagnostics was developed. The efficacy of neurosurgical treatment of pituitary adenomas at Cushing’s disease was estimated. 80 clinical cases of Cushing’s disease were analyzed. The adequate approaches to neurosurgical treatment of ACTH-producing pituitary adenomas depending on their size and propensity to invasion were certain.

References

Результаты хирургического лечения болезни Иценко-Кушинга / Б.А. Кадашев, Ю.К. Трунин, С.Ю. Касумова [и др.] // Вопр. нейрохирургии журн. им. Н.Н. Бурденко. — 1997. — №4. — С.7–12.

Марова Е.И. Болезнь Иценко–Кушинга / Е.И. Марова // Нейроэндокринология. — Ярославль, 1999. — С.81–145.

Мелькишев В.Ф. Диагностика и лечение аденом гипофиза. Оценка и выбор хирургических и нехирургических методов лечения: пособие для врачей // В.Ф. Мелькишев, В.Е. Олюшин, А.Ю. Улитин. — СПб., 2004. — 58 с.

A juvenile case of Cushing’s disease incidentally discovered with multiple bone fractures / A. Yoshihara, Y. Okubo, A. Tanabe [et al.] // Intern. Med. — 2007. — V.46, N9. — P.583–587.

Балаболкин М.И. Гипоталамо-гипофизарные заболевания / М.И. Балаболкин, Е.М. Клебанова // Эдокринология; под. ред. М.И. Балаболкина. — М.: Универсум пабл., 1998. — 582 с.

Опухоли хиазмально-селлярной области / Б.В. Гайдар, В.Р. Гофман, В.Ю. Черебилло [и др.] // Практическая нейрохирургия. — СПб., 2002. — С.446–475.

Pituitary adenomas with invasion of cavernous sinus: a magnetic resonanse imaging classification compared with surgical findings / E. Knosp, E. Steiner, K. Kitz [et al.] // Neurosurgery. — 1993. — V.33. — P.610–618.

Barakat M.T. Neuroendocrine tumors / M.T. Barakat, K. Meeran, S.R. Bloom // Endocr. Relat. Cancer. — 2004. — V.11. — P.1–18.

Saeger W. Current pathological classification of pituitary adenomas / W. Saeger // Acta Neurochir. — 1996. — V.65. — P.1–3.

Management of ACTH-secreting supradiaphragmatic adenomas / P. Dam-Hieu, B. Irthum, R. Seizeur [et al.] // Clin. Neurol. Neurosurg. — 2007. — V.109, N8. — P.698–704.

World Health Organization classification of tumors, pathology and genetics of tumors of endocrine organs / R.A. DeLellis, R.V. Lloyd, P.U. Heitz [et al.] — Lyon: IARC Press, 2004. — 320 p.

Location of ectopic adrenocortical hormone-secreting tumors causing Cushing’s syndrome in the paranasal sinuses / I. Hodish, T.J. Giordano, M.N. Starkman [et al.] // Head Neck. — 2009. — V.31, N5. — P.699 – 706

Published

2011-09-07

How to Cite

Guk, A., Voznyak, O., Guk, N., Pazyuk, V., Chuvashova, O., Salnikova, E., Zakordonets, V., Zemskova, O., Robak, K., Makeyev, S., & Danevych, O. (2011). Diagnosis аnd neurosurgical treatment of Cushing’s disease. Ukrainian Neurosurgical Journal, (3), 4–9. https://doi.org/10.25305/unj.57788

Issue

Section

Original articles