Cerebral blood flow and cerebral saturation in head injury. Comparison of CT perfusion and cerebral near-infrared oxymetry
Keywords:head injury, cerebral near-infrared oxymetry, perfusion computed tomography
Background. The purpose of this study was to determine the relationship between cerebral tissue oxygen saturation and cerebral blood volume in patients with traumatic brain injury.
Materials and methods. Perfusion computed tomography of the brain was performed in 27 patients with traumatic brain injury associated with simultaneous SctO2 level measurement using cerebral near-infrared oxymetry. The mean age of the injured persons was (34,5±15,5) years, 14 men, 13 women. The Injury Severity Score (ISS) values were 44,7±8,3 (25–81). The Glasgow Coma Score (GCS) mean value before the study was 10,3±1,9(5-13).
Results. SctO2 varied between 51 and 89%, mean (62,1±8,3)% (left frontal lobe) and (61,3±5,1)% (right frontal lobe). Cerebral blood volume (CBV) values were (2,3±0,63) ml/100 g, cerebral blood flow (CBF) was (31,7±13,4) ml/100 gЧmin, mean transit time (MTT) values were (5,3±3,4) s, the time to peak (TTP) was (21,2 ± 2,1) s.
Conclusions. Statistically significant correlation of SctO2 levels and cerebral blood volume (CBV) levels (P<0,000001) was found. There was no statistically significant correlation between brain tissue oxygenation and other parameters of the brain perfusion.
1. Frayerman AP, Kravets LYA, Trofimov AO. Sdavleniye golovnogo mozga pri izolirovannoy i sochetannoy cherepno-mozgovoy travme. N. Novgorod: OOO «Tipografiya «Povolzhye»; 2008. Russian. [eLIBRARY.ru].
2. Taussky P, ONeal B, Daugherty W et al. Validation of frontal near-infrared spectroscopy as noninvasive bedside monitoring for regional cerebral blood flow in brain-injured patients. Neurosurgical Focus. 2012;32(2):E2. [CrossRef] [PubMed]
5. Wintermark M1, Albers GW, Alexandrov AV, Alger JR, Bammer R, Baron JC, Davis S, Demaerschalk BM, Derdeyn CP, Donnan GA, Eastwood JD, Fiebach JB,Fisher M, Furie KL, Goldmakher GV, Hacke W, Kidwell CS, Kloska SP, Köhrmann M, Koroshetz W, Lee TY, Lees KR, Lev MH, Liebeskind DS, Ostergaard L,Powers WJ, Provenzale J, Schellinger P, Silbergleit R, Sorensen AG, Wardlaw J, Wu O, Warach S. Acute stroke imaging research roadmap. AJNR Am J Neuroradiol. 2008 May;29(5):e23-30. [PubMed]
6. Potapov AA, Korniyenko VN, Zakharova NE. Peculiarities of regional cerebral blood flow, intracranial pressure and cerebral perfusion pressure parameters in severe brain trauma. Luchevaya diagnostika i terapiya. 2012;3:79-92. Russian. [eLIBRARY.ru]
8. Griffith S, Caron JL, Coleman R. Invasive versus non-invasive monitoring of brain tissue oxygenation. Cerebrovasc. Dis. 2008;25:86.
9. Pott F, Gitte M. Cerebral blood volume in humans by NIRS and PET. Proc. SPIE. 1998;3194:306.
10. Miles K, Multidetector Computed Tomography In Cerebrovascular Disease. CT Perfusion Imaging. London:Informa UK; 2007.
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Copyright (c) 2013 Alexey Trofimov, Mikhail Yuriev, Oleg Voennov, Alexander Gribkov
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