Long-term results of surgical treatment of patients with tumors of III ventricle


  • Maksym Bazunov Cherkasy Regional Hospital, Cherkasy, Ukraine




III ventricle, tumors, surgical treatment, quality of life, survival rates


Purpose: to estimate results of treatment in patients with tumors of the III ventricle using neurosurgical interventions.

Materials and methods. The study is based on the results analysis of complex diagnostics and surgical treatment of 285 patients with tumors of III ventricle region in SI «Institute of Neurosurgery named after acad. A.P. Romodanov NAMS of Ukraine» in the period from 1993 to 2009.

Results. The influence of the tumor, the degree of radical removal of the tumor histological structure on quality of life (QOL) and survival of patients with tumors of the III ventricle was established. QOL improved after total removal of the tumor ventricle III - 80%, after subtotal - 57%, partial tumor removal - 60%.

For over 10 years lived 83% of patients after total removal of the tumor, 74% - after subtotal, 77% - after partial removal of the tumor.

Almost 90% of the patients survived more than 10 years after the removal of astrocytomas, regardless of its localization. This is significantly higher than after removal craniopharyngioma (up to 2 years lived 72% of patients, 5 years or longer - of about 62%); pineal parenchymal tumors (five years or longer lived 60%)  germ cell tumors (5 years lived 78%) . After total removal of colloid cysts, all patients were alive.

Conclusions. 1. Quality of life and survival rates in patients with tumors of the III ventricle region depend on tumor location, it’s radical removal and histological characteristics. 2. Total removal of tumors of the III ventricle region provided improving of quality of life in most patients. 3. The highest survival rates were achieved after total removal of tumors of the III ventricle region. 4. Survival rates after colloidal cysts and astrocytomas removing are higher than at other forms of tumors.

Author Biography

Maksym Bazunov, Cherkasy Regional Hospital, Cherkasy

Department of Neurosurgery


1. Grinberg MS. Neyrokhirurgiya [Neurosurgery]. Moscow: MEDpress-inform; 2010. Russian.

2. Kirichenko K.N. Diagnostika i khirurgicheskoye lecheniye kraniofaringiom u detey. Neyroendokrinnyye narusheniya v do- i posleoperatsionnom periodakh [Diagnosis and surgical treatment of craniopharyngiomas in children. Neuroendocrine disorders pre- and postoperative periods] [dissertation]. Sankt-Peterburg (Russia): Military Medical Academy; 2005. Russian.

3. Konovalov AN, Korniyenko VN, Pronin IN. Magnitno-rezonansnaya tomografiya v neyrokhirurgii [Magnetic resonance imaging in neurosurgery]. Moscow: Vidar; 1997. Russian.

4. Ellenbogen RG, Scott RM. Choroid plexus tumors. In: Winn HR, editor. Youmans Neurological Surgery; Philadelphia: Elsevier Inc., 2004. 5th ed;3(232) p.3612-22.

5. Kumar V, Behari S, Kumar Singh R, Jain M, Jaiswal A, Jain V. Pediatric colloid cysts of the third ventricle: management considerations. Acta Neurochir (Wien). 2009;152(3):451-61. [CrossRef] [PubMed]

6. Verbova LN. Diagnostika i khirurgicheskoye lecheniye opukholey oblasti III zheludochka [Diagnosis and surgical treatment of tumors of the region III ventricle] [dissertation]. Kiev (Ukraine): Romodanov Neurosurgery Institute; 1999. Russian.

7. Konovalov AN, Pitskhelauri DI. Lecheniye opukholey pineal'noy oblasti. Monografiya [Treatment of tumors of the pineal region. Monograph]. Moscow: OAO Mozhayskiy poligraf. komb.; 2004. Russian.

8. Rebrova OYu. Statisticheskiy analiz meditsinskikh dannykh. Primeneniye paketa prikladnykh programm STATISTICA [Statistical analysis of medical data. The use of the application package STATISTICA] Moscow: MediaSfera; 2002. Russian.

9. Al-Tamimi Y, Bhargava D, Surash S et al. Endoscopic biopsy during third ventriculostomy in paediatric pineal region tumours. Childs Nerv Syst. 2008;24(11):1323-26. [CrossRef] [PubMed]

10. Alen J, Boto G, Lagares A, de la Lama A, Gómez P, Lobato R. Intratumoural bleomycin as a treatment for recurrent cystic craniopharyngioma. Case report and review of the literature. Neurocirugía. 2002;13(6):479-85. [CrossRef] [PubMed]

11. Easwer H, Bhattacharya R, Nair S, Rao BR, Menon G, Abraham M, Kumar KK. Precoronal, paramedian minicraniotomy: a minimal access approach for microsurgical, transcallosal, transforaminal removal of colloid cysts of the third ventricle. Minim Invas Neurosurg. 2008;51(05):253-7. [CrossRef]

12. Hori T, Kawamata T, Amano K, Aihara Y, Ono M, Miki N. Anterior Interhemispheric Approach for 100 Tumors in and Around the Anterior Third Ventricle. Neurosurgery. 2010;66:65-74. [CrossRef] [PubMed]

13. Kleihues P, Cavenee W. Tumors of nervous System; Pathology and Genetics: World Health Organization International Classification of Tumors. Lyon, IARC Press, 2000.

14. Bruce JN, Connoly ES, Stein BM. Pineal and germ cell tumors. In: Kaye AH, Laws ER, editors. Brain tumors. An encyclopedic approach. London: Churchill Livingstone; 1995. p.725-55.

15. Caldarelli M, Massimi L, Tamburrini G, Cappa M, Di Rocco C. Long-term results of the surgical treatment of craniopharyngioma: the experience at the Policlinico Gemelli, Catholic University, Rome. Childs Nerv Syst. 2005;21(8-9):747-57. [CrossRef] [PubMed]

16. Deopuiari CE, Bivani N. Choroid plexus tumor. In: Kalangu K., editor. Essential Practice of Neurosurgery. Nagoya: Yamagiku Printing Co., Ltd; 2009. p.334-5.

17. Dzeytova AS. Opukholi parenkhimy shishkovidnogo tela: klinika, diagnostika i lecheniye [Tumors of the pineal parenchyma: clinical features, diagnosis and treatment] [dissertation]. Moscow (Russia0: Burdenko Neurosurgery Institute; 2006. Russian.

18. Tonn J-C, Westphal M, Rutka JT, Grossman SA, editors. Neuro-oncology of CNS tumors. Berlin: Springer; 2006.

19. Annamalai G, Lindsay K, Bhattacharya J. Spontaneous resolution of a colloid cyst of the third ventricle. Br J Radiol. 2008;81(961):20-2. [CrossRef] [PubMed]



How to Cite

Bazunov, M. (2013). Long-term results of surgical treatment of patients with tumors of III ventricle. Ukrainian Neurosurgical Journal, (3), 43–48. https://doi.org/10.25305/unj.54148



Original articles