Stereotactic radiosurgery at сavernous sinus meningiomas
Keywords:сavernous sinus meningioma, stereotactic radiosurgery
Introduction. The results of treatment of patients with cavernous sinus meningiomas, using stereotactic radiosurgery (SRS), were analyzed, the efficacy of the method was estimated.
Materials and methods. SRS, using linear accelerator Trilogy + BrainLab, was performed in 21 patients with сavernous sinus meningiomas. The target’s volume ranged from 2.13 to 12.57 cm3, the marginal dose — from 12 to 14 Gy, the target’s range, that received the marginal dose, was 70–99.4%, maximum dose — 13.8–19 Gy.
Results. In 15 patients in a period from 2 to 22 months (in average 10 months) after treatment MRI of the brain with intravenous contrast enhancement was conducted, in 93.3% of them negative dynamic in neurological status was not observed, in 53.3% patients there was tumor size reduction, in 40% — it’s sizes stabilization, in 93.3% — the control of tumor growth was achieved.
Conclusions. SRS — is an effective and safe method of treatment of сavernous sinus meningiomas, in the first year of observation it provides a high (93.3%) level control of tumor growth without neurologic worsening.Using lower doses (12–12.5 Gy) reduces the likelihood of transient and permanent neurological worsening without violating of tumor growth control.
1. dos Santos M, de Salcedo J, Gutiérrez Diaz J Calvo FA, Samblás J, Marsiglia H, Sallabanda K. Long-term outcomes of stereotactic radiosurgery for treatment of cavernous sinus meningiomas. Int J Radiat Oncol Biol Phys. 2011;81(5):1436-41. [CrossRef] [PubMed]
2. Galkin MV. Stereotaksicheskaya luchevaya terapiya v lechenii meningiom medial'nykh otdelov sredney cherepnoy yamy [Stereotactic radiotherapy in the treatment of meningiomas of medial of middle cranial fossa] [dissertation]. Moscow (Russia): Burdenko Neurosurgery Institute; 2011. Russian.
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Copyright (c) 2013 Olga Chuvashova, Irina Kruchok
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