Opportunities of modern single photone emission computed tomography in diagnostics of the focal epilepsy

Authors

  • Sergiy Makeyev Nuclear Medicine Department, Romodanov Neurosurgery Institute, Kiev, Ukraine

Keywords:

single photon emission computed tomography (SPECT), 99mTc-HMPAO, focal epilepsy, cerebral perfusion

Abstract

The application of single photone emission computed tomography (SPECT) with perfuision radiopharmaceuticals (99mTc-HMPAO) has allowed to expand opportunities of nuclear medicine in diagnostics of the focal brain pathology, including focal epilepsy. Thirty two patients with clinical symptoms of epilepsy were underwent 99mTc-HMPAO SPECT. At a part of these patients was investigated also by EEG, CT and MRI. The general informativity was: SPECT — 84,4%, EEG — 90 %, CT — 52,2 %, MRI — 83,3%. The higher accuracy SPECT in diagnostics of localization of epilepsy focus in comparison with EEG was proven. Best informativity was reached with complex using of various methods of diagnostics.

References

Abdel-Dayem H.M., Nawaz K., Hassoon M., Rahman M., Olofsson O.E. Cerebral perfusion abnormalities in therapy-resistant epilepsy in mentally retarded pediatric patients. Comparison with EEG and X-ray CT. Anon.-76th scientific assembly and annual meeting of the Radiological Society of North America.Oak Brook,IL(USA).—1990.— 331p.: 218.

Chung J. K., Kim E. S., Lee K. H., Lee S. G., Lee M.C., Koh C.S. Ictal 99mTc-HMPAO SPECT compared with video EEG monitoring and MRI in localizing the neocortical epileptogenic region. Inter. Symp. on tomography in nucl. med.. Proc. Іnter. Symp., IAEA, Vienna.—1996.— 453 p.: 315—320.

Duncan R. Ictal/postictal SPECT in the pre-surgical localisation of complex partial seizures. J. of Neurol., Neurosurg. and Psyc.—1993.—N56.—P.141—148.

Nagata T., Tanaka F., Yonekura Y. Limited value of interictal brain perfusion SPECT for detection of epileptic foci. High resolution SPECT studies in comparison with FDG-PET// Ann. of Nucl. Med.— 1995.—№ 9(2).—P.59—63.

Rodrigues M., Botelho M.M., Fonseca A.T., Peter J.P., Pimentel T., Vieira M.R. Combined study of 99mTc-HMPAO SPECT and computerized electroencephalographic topography (CET) in patients with medically refractory complex partial epilepsy. Ann. of Nucl. Med.— 1996.—N10(1)— P.113—118.

Runge U; Kirsch G; Petersen B; Kallwellis G; Gaab MR; Piek J; Kessler C. Ictal and interictal ECD-SPECT for focus localization in epilepsy // Acta Neurol Scand.— N96(5).—1997.—P.271—276.

Setoain FJ; Arroyo S; Lomena F; Pavґia J; Martinez I; Fuster D; Herranz R. Setoain //1.Single photon emission computed tomography SPECT in a patient with bilateral temporal seizures: correlation between ictal EEG and postictal/ictal SPECT// Epilepsia.— 1998.—N39(9).—P.1001—1005.

Yamaga L.Y. I., Buchpiguel C.A., Hironaka F.H., Dias Neto A.L., Yacubian E., Valerio R., Jorge C. Contribution of 99mTc-HMPAO SPECT in the evaluation of temporal lobe epilepsy. International symposium on tomography in nuclear medicine. Tomography in nuclear medicine. Proc. Inter. Symp., IAEA, Vienna.— 1996.—453p.: 335—345.

Zahlava J., Salcmanova Z. Experience with 99mTc-HMPAO brain SPECT in epileptic patients. International symposium on tomography in nuclear medicine. Proc. Inter. Symp., IAEA, Vienna.—1996.—453 p.: 309—314.

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How to Cite

Makeyev, S. Opportunities of modern single photone emission computed tomography in diagnostics of the focal epilepsy. Ukrainian Neurosurgical Journal, (3), 88–90. Retrieved from https://theunj.org/article/view/53034

Issue

No. 3 (2000)

Section

Original articles

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Copyright (c) 2000 Sergiy Makeyev

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