Features of antibacterial therapy of nosocomial pneumonia in injures persons in the early period of traumatic brain injury
Keywords:early period of TBI, hospital-acquired pneumonia, antibacterial therapy, risk factors
Introduction. Hospital-acquired pneumonia (HAP) significantly complicates post-operative and posttraumatic period in patients in early period of traumatic brain injury (TBI). The purpose of the study was to study features of HAP course and antibacterial therapy (ABT) in patients with TBI been treated in neurosurgical (intensive care) unit of Kyiv City Emergency Hospital.
Materials and methods. A prospective clinical and microbiological study of infectious and inflammatory processes (HAP) in injured persons in the early period of TBI was provide on the base of neurosurgical (intensive care) unit of Kyiv City Emergency Hospital.
Results. HAP was diagnosed in 76 patients with isolated severe and moderate-severe TBI in the early period. Respiratory pathogens structure was identified, features of HAP course and impact of risk factors were studied, effectiveness of empirical etiotropic ABT was estimated in patients in the early period of TBI.
Conclusions. High efficiency of etiotropic application of antibiotics in comparison with empirical ABT was established. The risk factors complicating TBI clinical course were defined.
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