Surgical tactics and treatment results at spinal lymphomas

Authors

  • Eugene Slynko Spinal Department, Romodanov Neurosurgery Institute, Kiev, Ukraine
  • Anatoliy Pastushin Spinal Department, Romodanov Neurosurgery Institute, Kiev, Ukraine
  • Tatyana Malysheva Department of Pathomorphology, Romodanov Neurosurgery Institute, Kiev, Ukraine
  • Oksana Chernenko Department of Pathomorphology, Romodanov Neurosurgery Institute, Kiev, Ukraine

DOI:

https://doi.org/10.25305/unj.51298

Keywords:

non-Hodgkin’s lymphomas, Hodgkin’s lymphomas, spinal cord, surgical treatment

Abstract

The purpose — to study features of lymphomas affecting spinal cord and it’s membranes, to develop rational tactics for their treatment.

Material and methods. 9 patients with spinal lymphomas were examined. All patients have been operated, the diagnosis was verified histologically. Preoperative diagnostics was based on clinical data and neurological examination, X-ray, MRI. Electroneuromyography was performed in 5 patients, bone scintigraphy — in 3.

Results. Two main localization of lymphomas were identified: I — intramedullar lesion, and II — lesion of dura mater of the spinal cord with epidural, subdural or epi-subdural spread. In 3 cases intramedullar lesion was revealed, in 6 — lesion of dura mater of the spinal cord.

Conclusions. There are tumors that primary affects the spinal cord or it’s dura mater. Tumors affecting the spinal cord, non-Hodgkin’s lymphomas as a rule are the primary. Tumors affecting spinal dura mater are Hodgkin’s lymphoma, and usually are the secondary, they manifested after prolonged conservative treatment. The histological diagnosis of lymphoma should be confirmed by immunohistochemical studies. Tactics of treatment at spinal lymphomas with neurological manifestations should be directed to their removal, decompression of spinal cord followed by radiotherapy, chemotherapy and corticosteroid therapy if necessary.

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Published

2014-06-09

How to Cite

Slynko, E., Pastushin, A., Malysheva, T., & Chernenko, O. (2014). Surgical tactics and treatment results at spinal lymphomas. Ukrainian Neurosurgical Journal, (2), 29–35. https://doi.org/10.25305/unj.51298

Issue

Section

Original articles