Improving diagnostic informative of stereotactic biopsy through technology of combining multimodal imaging at focal brain lesions

Authors

  • Iaroslav Zinkevych Centre of General Neurosurgery, Clinical Hospital «Feofaniya», Kyiv, Ukraine
  • Volodymyr Rozumenko Department of Intracerebral Tumors, Romodanov Neurosurgery Institute, Kiev, Ukraine
  • Olga Chuvashova Department of Neuroradiology and Radioneurosurgery, Romodanov Neurosurgery Institute, Kiev, Ukraine
  • Tatyana Malysheva Neuropathomorphology Department, Romodanov Neurosurgery Institute, Kiev, Ukraine
  • Artem Rozumenko Department of Intracerebral Tumors, Romodanov Neurosurgery Institute, Kiev, Ukraine
  • Sergiy Makeyev Nuclear Medicine Department, Romodanov Neurosurgery Institute, Kiev, Ukraine
  • Vitaliy Tsymbaliuk Department of Restorative Neurosurgery, Romodanov Neurosurgery Institute, Kiev, Ukraine https://orcid.org/0000-0001-7544-6603

DOI:

https://doi.org/10.25305/unj.46606

Keywords:

focal brain lesions, diagnostic, multimodal approach, stereotactic biopsy, MR-spectroscopy, perfusion computed tomography, SPECT

Abstract

Purpose. Developing and clinical testing of effective technology of multimodal images combining and use of additional neuroimaging methods for differentiated diagnostics, coordinates determination and trajectories for stereotactic biopsy (STB), optimal target zone, STB diagnostic informative increasing.

Materials and methods. 339 patients with focal brain lesions were included in our study. Stereotactic intervention was performed using stereotactic system CRW Radionics with software StereoFusion, StereoPlan (Radionics) for coordinates calculation. Statistical analysis of the data was performed using nonparametric methods.

Results. STB planning before operation was done by MSCT and MRI fusion for maximum information content of diagnostics. MRI and MSCT images fusion was done in 282 (83.2%) cases (group A), multi-modal images comparison (emission computed tomography, MRI-spectroscopy and MSCT-perfusion) — in 57 (16.8%) patients (group B).

Conclusions. Optimal diagnostic algorithm should include standard MSCT and MRI with contrast enhancement, MR-spectroscopy, emission tomography and computed tomography perfusion. Multimodal technology improved STB diagnostic informative at focal brain lesion.

References

Grosu A, Lachner R, Wiedenmann N et al. Validation of a method for automatic image fusion (BrainLAB System) of CT data and 11C-methionine-PET data for stereotactic radiotherapy using a LINAC: first clinical experience. International Journal of Radiation Oncology*Biology*Physics. 2003;56(5):1450-1463. CrossRef

Pietrzyk U, Herholz K, Schuster A, Stockhausen H, Lucht H, Heiss W. Clinical applications of registration and fusion of multimodality brain images from PET, SPECT, CT, and MRI. European Journal of Radiology. 1996;21(3):174-182. CrossRef

Sui J, Adali T, Yu Q, Chen J, Calhoun V. A review of multivariate methods for multimodal fusion of brain imaging data. Journal of Neuroscience Methods. 2012;204(1):68-81. CrossRef

Hill D, Batchelor P, Holden M, Hawkes D. Medical image registration. Physics in Medicine and Biology. 2001;46(3):R1-R45. CrossRef

Rozumenko VD, Rozumenko AV. [Multimodal neuronavigation using in surgery of brain tumors]. Ukr Neurosurg J. 2010;(4):51–57. Russian.

Klinichni protokoly nadannya medychnoyi dopomohy za spetsialnostyamy «neyrokhirurhiya» ta «dytyacha neyrokhirurhiya». Ukr Neurosurg J. 2008;(3):115–117. Ukrainian.

Barker P. Clinical MR Spectroscopy. Cambridge: Cambridge University Press; 2010.

Horská A, Barker P. Imaging of Brain Tumors: MR Spectroscopy and Metabolic Imaging. Neuroimaging Clinics of North America. 2010;20(3):293-310. CrossRef

Jain R. Perfusion CT Imaging of Brain Tumors: An Overview. American Journal of Neuroradiology. 2010;32(9):1570-1577. CrossRef

Mintser O, Voronenko YU, Mintser O. Obroblennya klinichnykh i eksperymentalnykh danykh u medytsyni: navch. posibnyk. Kiev: Vyshcha shk., 2003. Ukrainian.

Downloads

Published

2014-12-24

How to Cite

Zinkevych, I., Rozumenko, V., Chuvashova, O., Malysheva, T., Rozumenko, A., Makeyev, S., & Tsymbaliuk, V. (2014). Improving diagnostic informative of stereotactic biopsy through technology of combining multimodal imaging at focal brain lesions. Ukrainian Neurosurgical Journal, (4), 71–77. https://doi.org/10.25305/unj.46606

Issue

No. 4 (2014)

Section

Original articles

License

Copyright (c) 2014 Iaroslav Zinkevych, Volodymyr Rozumenko, Olga Chuvashova, Tatyana Malysheva, Artem Rozumenko, Sergiy Makeyev, Vitaliy Tsymbaliuk

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

Ukrainian Neurosurgical Journal abides by the  CREATIVE COMMONS copyright rights and permissions for open access journals.

Authors, who are published in this Journal, agree to the following conditions:

1. The authors reserve the right to authorship of the work and pass the first publication right of this work to the Journal under the terms of Creative Commons Attribution License, which allows others to freely distribute the published research with the obligatory reference to the authors of the original work and the first publication of the work in this Journal.

2. The authors have the right to conclude separate supplement agreements that relate to non-exclusive work distribution in the form of which it has been published by the Journal (for example, to upload the work to the online storage of the Journal or publish it as part of a monograph), provided that the reference to the first publication of the work in this Journal is included.