Role of stereotactic radiosurgery in treatment of patients with posterior fossa meningiomas
Keywords:posterior fossa meningioma, stereotactic radiosurgery
The purpose. To analyze treatment results of patients’ with posterior fossa meningiomas using stereotactic radiosurgery (SRS), to estimate efficacy of the method.
Materials and methods. SRS, using linear accelerator «Trilogy + BrainLab» was performed in 51 patients with posterior fossa meningiomas. The target’s volume ranged from 0.85 to 19.2 cm3, the marginal dose — from 11 to 15 Gy, target’s volume, received the marginal dose — from 81 to 100%, maximum dose — 12.7–20 Gy. 36 patients were followed from 2 to 36 months, in average 12.3 months after treatment.
Results. According to SRS efficacy estimation and neurological status there was no dynamic in 88.9% patients. MRI results showed tumor decrease in 44.4% cases, it’s stabilization — in 52.8%, tumor’s growth control was achieved in 97.2% patients.
Conclusions. SRS is an effective and safe method of treatment of posterior fossa meningiomas, providing high rate (97.2%) of tumor’s growth control and ensuring high quality of patients’ life (Karnofsky index over 80).
SRS with lower marginal doses (12–12.7 Gy) reduces frequency (in 88.9% cases) of transient and permanent neurological deficit, without changing conditions for tumor’s growth control.
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Copyright (c) 2014 Irina Kruchok, Olga Chuvashova, Lyudmila Verbova
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