A clinical dilemma for treatment choice of extramedullary spinal plasmacytoma in patients with multiple myeloma: chemotherapy or surgery? A double-case clinical report

Authors

  • Tetiana V. Lymanets Internal Medicine №1 Department, Poltava State Medical University, Poltava; Hematology Department, Communal Enterprice “Poltava Regional Clinical Hospital n.a. M.V. Sklifosovsky Poltava Regional Council”, Poltava, Ukraine https://orcid.org/0000-0001-6021-7066
  • Ganna S. Maslova Internal Medicine №1 Department, Poltava State Medical University, Poltava, Ukraine http://orcid.org/0000-0002-4729-1736
  • Yelizaveta O. Stadnik Internal Medicine №1 Department, Poltava State Medical University, Poltava, Ukraine https://orcid.org/0009-0006-1598-3443
  • Iuliia O. Gusachenko Hematology Department, Communal Enterprice “Poltava Regional Clinical Hospital n.a. M.V. Sklifosovsky Poltava Regional Council”, Poltav, Ukraine https://orcid.org/0009-0005-3195-547X
  • Oleksandr L. Havlovskyi Neurosurgery Department, Communal Enterprice “Poltava Regional Clinical Hospital n.a. M.V. Sklifosovsky Poltava Regional Council”, Poltava, Ukraine https://orcid.org/0000-0002-7799-9938

DOI:

https://doi.org/10.25305/unj.349396

Keywords:

multiple myeloma, spinal cord plasmacytoma, soft tissue extramedullary disease, chemotherapy

Abstract

Two presented case reports that highlight extramedullary spinal cord plasmacytomas in patients with diagnosed multiple myeloma are intended to change the paradigm of understanding the indication of surgical intervention. In the first case, the condition manifested as a relapse of kappa light chain multiple myeloma, whereas in the second case, it emerged as a primary manifestation of the same disease. Both patients received a combination chemotherapy of bortezomib, lenalidomide, and dexamethasone, which proved to be highly effective, eliminating the need for surgical intervention.

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Published

2026-06-30

How to Cite

Lymanets, T. V., Maslova, G. S., Stadnik, Y. O., Gusachenko, I. O., & Havlovskyi, O. L. (2026). A clinical dilemma for treatment choice of extramedullary spinal plasmacytoma in patients with multiple myeloma: chemotherapy or surgery? A double-case clinical report. Ukrainian Neurosurgical Journal, 32(2), 112–118. https://doi.org/10.25305/unj.349396

Issue

Vol. 32 No. 2 (2026)

Section

Case Report

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Copyright (c) 2026 Tetiana V. Lymanets, Ganna S. Maslova, Yelizaveta O. Stadnik, Iuliia O. Gusachenko, Oleksandr L. Havlovskyi

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