Сavernous malformations of the brain in children (literature review and report of personal cases)

Authors

  • Yu. A. Orlov Romodanov Neurosurgery Institute, Kiev, Ukraine
  • M. Yu. Orlov Romodanov Neurosurgery Institute, Kiev, Ukraine

Keywords:

cavernous malformation, brain, children, diagnosis, treatment

Abstract

The article represents review of literature and analysis of 34 personal cases of cerebral cavernomas malformation in children. Paper discusses the variants of clinical presentation, modern methods of diagnostic and treatment, based on the patient’s condition, lesion localization, on the severity of hemorrhage, mass effect and dislocation syndrome. The results of surgical treatment of “hemispheric” cavernomas can be admitted as good, meanwhile the cavernomas of brain stem and subcortical localisation need further elaboration.

References

Ватолин К.В. Ультразвуковая диагностика заболеваний головного мозга у детей. — М.: Видар, 1995. — 120 с.

Зозуля Ю.А., Слынько Е.И. Спинальные сосудистые опухоли и мальформации. — К.: ООО УВПК ЕксОб, 2000 . — 375 с.

Иова А.С., Гармашов Ю.А., Андрющенко Н.В., Паутницкая Т.С. Ультрасонография в нейропедиатрии (новые возможности и перспективы): Ультрасонографический атлас. — СПб.: Петроградский и К., 1997. — 160 с.

Скороморец А.А., Тиссен Т.П., Панюшкин A.И., Скороморец Т.А. Сосудистые заболевания спинного мозга. — СПб.: Сотис, 1998. — 526 с.

Abe T., Singer R.J., Marks M.P. et al. Coexistence of occult vascular malformations and developmental venous anomalies in the central nervous system: MR evaluation //Amer. J. Neuroradiol. — 1998. — V.19. — P.51–57.

Abdulrauf S.I., Awad I.A. Comment about the article of Amin-Hanjani S et al. //Neurosurgery. — 1998. — V.42. — P.1227.

Awad I.A., Robinson J.R., Mohanty S., Estes M.L. Mixed vascular malformations of the brain: clinical and pathogenetic considerations //Neurosurgery. — 1993. — V.33. — P.179–188.

Ball W.S. Jr. (1997) Cerebrovascular disease. In: Ball W.S. Jr. (ed) Pediatric neuroradiology. — Lippincott-Raven, Philadelphia, 1997. — P.505–563.

Barrow D.L., Krisht A. Cavernous malformations and hemorrhage / Awad I.A., Barrow D.L. (eds) Cavernous malformations. — AANS Publications Committee, Park Ridge, 1993. — P.65–80.

Barrow D.L., Awad I.A. Conceptual overview and management strategies. / Awad I.A., Barrow D.L. (eds) Cavernous malformations. — AANS Publications Committee, Park Ridge, 1993. — P.205–213.

Brühl K., Humpl T., Gutjahr P. et al. Cerebral cavernomas and telangiectasias as secondary disease following acute lymphatic leukaemia and cranial irradiation //Neuroradiology. — 1995. — V.37. — Suppl. 1. — P.54.

Buckingham M.J., Crone K.R., Ball W.S., Berger T.S. Management of cerebral cavernous angiomas in children presenting with seizures //Child’s Nerv. Syst. — 1989. — V.5. — P.347–349.

Cavalheiro S., Braga F.M. Cavernous hemangiomas / Choux M., Di Rocco C., Hockley A.D., Walker M.L. (eds) Pediatric neurosurgery. — Churchill Livingstone, London, 1999. — P.691–701.

Curling O.D., Kelly D.L., Elster A.D., Craven T.E. An analysis of the natural histoy of cavernous angiomas //J. Neurosurg. — 1991. — V.75. — P.702–708.

De Tribolet N., Kaech D., Perentes E. Cerebellar haematoma due to a cavernous angioma in a child //Acta Neurochir. (Wien). — 1982. — V.60. — P.37–43.

Dillon W.P. Cryptic vascular malformations: controversies in terminology, diagnosis, pathophysiology, and treatment //Amer. J. Neuroradiol. — 1997. — V.18. — P.1839–1846.

Di Rocco C., Ianelli A., Tamburrini G. Cavernomas of the central nervous system in children. A report of 22 cases //Acta Neurochir. (Wien). — 1996. — V.138. — P.1267–1274.

Dubovsky J., Zabramski J.M., Kurth J. et al. A gene responsible for cavernous malformations of the brain maps to chromosome 7q //Hum. Molec. Genet. — 1995. — V.4. — P.453–458.

Edwards M.S.B., Baumgartner J.E., Wilson C.B. Cavernous and other cryptic vascular malformations in the pediatric age group / Awad I.A., Barrow D.L. (eds) Cavernous malformations. — AANS Publications Committee, Park Ridge, 1993. — P.163–183, 185–186.

Fortuna A., Ferrante L., Mastronardi L. et al. Cerebral cavernous angioma in children //Childs. Nerv. Syst. — 1989. — V.5. — P.201–207.

Gangemi M., Longatti P., Maiuri F. et al. Cerebral cavernous angiomas in the first year of life //Neurosurgery. — 1989. — V. 25. — P.465–469.

Gil-Nagel A., Dubovsky J., Wilcox K.J. et al. Familial cerebral cavernous angioma: a gene localized to a 15-cM interval on chromosome 7q //Ann. Neurol. — 1996. — V39. — P.807–810.

Gunel M., Awad I.A., Finberg K. et al. A founder mutation as a cause of cerebral cavernous malformation in Hispanic Americans //New Engl. J. Med. — 1996. — V.334. — P.946–951.

Gunel M., Awad I.A., Finberg K. et al. Genetic heterogeneity of inherited cerebral cavernous malformation //Neurosurgery. — 1996. — V.38. — P.1265–1271.

Hatashita S., Miyajima M., Kogan N. Cystic cavernous angioma. Case report //Neurol. Med. Chir. — 1991. — V.31. — P.414–416.

Heckl S., Aschoff A., Kunze S. Radiation-induced cavernous hemangiomas of the brain: a late effect predominantly in children //Cancer. — 2002. — V.94. — P.3285-3291.

Hermier M., Ongolo-Zogo P., Levrel J.M. et al. Spontaneous cerebral hematomas in children complicating unsuspected vascular malformations: value of the morphological analysis in the differential diagnosis between cerebral cavernoma (CM) and arteriovenous malformation (AVM) 35th Annual Congress of the European Society for Pediatric Radiology. — Rhodes, Greece, 1998 — P.78.

Herter T., Brandt M., Szüwart U. Cavernous hemangiomas in children //Childs. Nerv. Syst. — 1988. — V.4. — P.123–127.

Hotteville J.P. The surgery of cavernomas, both supratentorial and infratentorial //Adv. Techn. Stand. Neurosurg. — 1995. — V.22. — P.185—259.

Hsu F.P.K., Rigamonti D., Huhn S.L. Epidemiology of cavernous malformations / Awad I.A., Barrow D.L. (eds) Cavernous malformations. — AANS Publications Committee, Park Ridge, 1993. — P.13–23.

Hubert P., Choux M., Houtteville J.P. Cavernomes cérébraux de l’enfant et du nourrisson //Neurochirurgie. — 1989. — V.35. — P.104–105.

Huhn S.L., Rigamonti D., Hsu F. Indications for surgical intervention. In: Awad IA, Barrow DL (eds) Cavernous malformations. — AANS Publications Committee, Park Ridge, 1993. — P. 87–99.

Kim D.S., Park Y.G., Choi J.U. et al. An analysis of the natural history of cavernous malformations //Surg. Neurol. — 1997. — V.48. — P.9–18.

Kondziolka D., Lunsford L.D., Kestle J.R. The natural history of cerebral cavernous malformations //J. Neurosurg. — 1995. — V.83. — P. 820–824.

Labauge P., Laberge S., Brunereau L. et al. Hereditary cerebral cavernous angiomas: clinical and genetic features in 57 french families //Lancet. — 1998. — V.352. — P.1892–1897.

Lapras C.l., Lapras Ch., Deruty R. et al. Traitement chirurgical des cavernomes intracérébraux //Neurochirurgie. — 1989. — V.35. — P.120–125.

Latchaw R.E., Truwit C.L., Heros R.C. Venous angioma, cavernous angioma, and hemorrhage //Amer. J. Neuroradiol. — 1994. — V.15. — P.1255–1257.

Leblanc R., Little J.R. Hemodynamics of arteriovenous malformations //Clin. Neurosurg. — 1989. — V.36. — P.299–317.

Lechevalier B. Etude neuropathologique des cavernomes //Neurochirurgie. — 1989. — V.35. — P.78–81.

Le Doux M.S., Aronin P.A., Odrezin G.T. Surgically treated cavernous angiomas of the brainstem: report of two cases and review of the literature //Surg. Neurol. — 1991. — V.35. — P.395–399.

Lena G., Paz Paredes A., Choux M. Brain stem cavernomas in children. Nine case reports and literature review //J. Neurochirurgie. — 2002. — V.48. — P.319—325.

Lieberman M.W., Lebovitz R.M. Neoplasia in Kissane J.M. (ed.): Anderson’s Pathology. — St. Louis, CV Mosby Company, 1990. — V.9. — P.570—575.

Little J.R., Awad I.A., Jones S.C., Ebrahim Z.Y. Vascular pressures and cortical blood flow in cavernous malformation of the brain //J. Neurosurg. — 1990. — V.73. — P.555–559.

Maraire J.N., Awad I.A. (1995) Intracranial cavernous malformations: lesion behavior and management strategies //Neurosurgery. — 1995. — V.37. — P.591–605.

Mazza C., Scienza R., Dalla Bernardin B. et al. Malformations caverneuses cérébrales (cavernomes) de l’enfant //Neurochirurgie. — 1989. — V.35. — P.106– 108.

Mazza C., Scienza R., Beltramello A., Da Pian R. Cerebral cavernous malformations (cavernomas) in the pediatric age group //Childs. Nerv. Syst. — 1991. — V.7. –P.139–146.

Morales G., Escalonilla G.,Galan L. et al. Cerebral cavernomas in childhood, clinical presentation and diagnosis //Rev. Neurol. — 2002. — V.34. — P.339—342.

Moriarty J.L., Wetzel M., Clatterbuck R.E. et al. The natural history of cavernous malformations: a prospective study of 68 patients //Neurosurgery. — 1999. — V.44. — P.1166–1173.

Mottorese C., Hermier M., Stan H. et al. Central nervous system cavernomas in the pediatric age group //Neurosurg. Rev. — 2001. — V.24. — P.55-71.

Nakasu S., Yoshida M., Nakajima M., Handa J. (1991) Cystic cavernous angioma in an infant: CT features //J. Comput. Assist. Tomogr. — 1991. — V.15. — P.163–165.

How to Cite

Orlov, Y. A., & Orlov, M. Y. Сavernous malformations of the brain in children (literature review and report of personal cases). Ukrainian Neurosurgical Journal, (4), 38–45. Retrieved from https://theunj.org/article/view/145013

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Section

Original articles