Olfactory ensheathing cells potential effectiveness in spinal cord and peripheral nerves injury recovery treatment

Authors

  • V. I. Tsymbalyuk Romodanov Neurosurgery Institute, Kiev, Ukraine
  • V. M. Semenova Romodanov Neurosurgery Institute, Kiev, Ukraine
  • Yu. Ya. Yaminsky Romodanov Neurosurgery Institute, Kiev, Ukraine
  • V. V. Medvedev Romodanov Neurosurgery Institute, Kiev, Ukraine

DOI:

https://doi.org/10.25305/unj.128189

Keywords:

olfactory bulb, Olfactory ensheathing cells, neurogenic stem cells, cell transplantation, spinal cord injury

Abstract

Modern conceptions of mammalian olfactory ensheathing cells (OEC) properties are presented. Taking into consideration an important role of this cell type in ensuring axons of receptor neurons’ into olfactory bulb tissue growth, some experimental data on OEC application for transplantation effectiveness and it’s perspectives for the aim to restore the spinal cord and peripheral nerves conduction are listed.

References

Barnett S.C., Alexander C.L., Iwashita Y. et al. Identification of a human olfactory ensheathing cell that can effect transplant-mediated remyelination of demyelinated CNS axons // Brain. — 2000. — V.123. — P.1581–1588.

Beites C.L., Kawauchi S., Crocker C.E., Calof A.L. Identification and molecular regulation of neural stem cells in the olfactory epithelium // Exp. Cell. Res. — 2005. — V.306, N2. — P.309–316.

Boyd J.G., Lee J., Skihar V. et al. LacZ-expresing olfactory ensheathing cells do not associate with myelinated axons after implantation into the compressed spinal cord // PNAS. — 2004. — V.101, N7. — P.2162–2166.

Boyd J.G., Jahed A., McDonald T.G. et al. Proteomic evaluation reveals that olfactory ensheathing cells but not Schwann cells express calponin // Glia. — 2006. — V.53, N4. — P.434–440.

Cheng S.Y., Ruan H.Z., Wu X.G. Olfactory ensheathing cells enhance functional recovery of injured sciatic nerve (abstract) // Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi. — 2003. — V.17, N1. — P.18–21.

Chuah M.I., Au C. Olfactory cells cultures on ensheathing cells monolayers // Chem. Senses. — 1994. — V.19. — P.25–34.

Chuah M.I., Choi-Lundberg D., Weston S. et al. Olfactory ensheathing cells promote collateral axonal branching in the injured adult rat spinal cord // Exp. Neurol. — 2004. — V.185, N1. — P.15–25.

Collazos-Castro J.E., Muneton-Gomez V.C., Nieto-Sampedro M. Olfactory glia transplantation into cervical spinal cord contusion injuries // J. Neurosurg. Spine. — 2005. — V.3, N4. — P.308–317.

Feron F., Mackay-Sim A., Andrieu J.L. et al. Stress induces neurogenesis in non-neuronal cell cultures of adult olfactory epithelium // Neuroscience. — 1999. — V.88. — P.571–583.

Fouad K., Schnell L., Bunge M.B. et al. Combining Schwann cell bridges and olfactory-ensheathing glia grafts with chondroitinase promotes locomotor recovery after complete transection of the spinal cord // J. Neuroscience. — 2005. — V.25, N5. — P.1169–1178.

Franceschini I.A., Barnett S.C. Low-affinity NGF-receptor and E-N-CAM expression define two types of olfactory nerve ensheathing cells that share a common lineage // Dev. Biol. — 1996. — V.173. — P.327–343.

Gomez V.M., Averill S., King V. et al. Transplantation of olfactory ensheathing cells fails to promote significant axonal regeneration from dorsal roots into the rat cervical cord // J. Neurocytol. — 2003. — V.32, N1. — P.53–70.

Huang H., Chen L., Wang H. et al. Influence of patients' age on functional recovery after transplantation of olfactory ensheathing cells into injured spinal cord injury // Chin. Med. J. (Engl). — 2003. — V.116, N10. — P.1488–1491.

Imaizumi T., Lankford K.L., Waxman S.G. et al. Transplanted olfactory ensheathing cells remyelinate and enhance axonal conduction in the demyelinated dorsal columns of the rat spinal cord // J. Neurosci. — 1998. — V.18, N16. — P.6176–6185.

Keyvan-Fouladi N., Raisman G., Li Y. Functional repair of the corticospinal tract by delayed transplantation of olfactory ensheathing cells in adult rats // J. Neurosci. — 2003. — V.23, N28. — P.9428–9434.

Kumar R., Hayat S., Felts P. et al. Functional differences and interactions between phenotypic subpopulations of olfactory ensheathing cells in promoting CNS axonal regeneration // Glia. — 2005. — V.50, N1. — P.12–20.

Lakatos A., Barnett S.C., Franklin R.J. Olfactory ensheathing cells induce less host astrocyte response and chondroitin sulphate proteoglycan expression than Schwann cells following transplantation into adult CNS white matter // Exp. Neurol. — 2003. — V.184, N1. — P.237–246.

Li Y., Field P.M., Raisman G. Repair of adult rat corticospinal tract by transplants of olfactory ensheathing cells // Science. — 1997. — V.277. — P.2000–2002.

Li Y., Carlstedt T., Berthold C.H., Raisman G. Interaction of transplanted olfactory-ensheathing cells and host astrocytic processes provides a bridge for axons to regenerate across the dorsal root entry zone // Exp. Neurol. — 2004. — V.188, N2. — P.300–308.

Li Y., Sauve Y., Li D. et al. Transplanted olfactory ensheathing cells promote regeneration of cut adult rat optic nerve axons // J. Neurosci. — 2003. — V.23, N21. — P.7783–7788.

Lu J., Feron F., Mackay-Sim A., Waite P.M.E. Olfactory ensheathing cells promote locomotory recovery after delayed transplantation into transected spinal cord // Brain. — 2002. — V.125, N1. — P.14–21.

Lu J., Feron F., Ho S.M. et al. Transplantation of nasal olfactory tissue promotes partial recovery in paraplegic adult rats // Brain Res. — 2001. — V.889. — P.344–357.

Mackay-Sim A., Chuah M.I. Neurotrophic factors in the primary olfactory pathway // Prog. Neurobiol. — 2000. — V.62. — P.527–559.

Novikova L.N., Mosahebi A., Wiberg M. et al. Alginate hydrogel and matrigel as potential cell carriers for neurotransplantation // J. Biomed. Mater. Res. A. — 2006. — V.77, N2. — P.242–252.

Pagano S., Impagnatiello F., Girelli M. et al. Isolation and characterization of neural stem cells from the adult human olfactory bulb // Stem Cells. — 2000. — V.18, N4. — P.295–300.

Pearse D.D., Marcillo A.E., Oudega M. et al. Transplantation of Schwann cells and olfactory ensheathing glia after spinal cord injury: does pretreatment with methylprednisolone and interleukin-10 enhance recovery? // J. Neurotrauma. — 2004. — V.21, N9. — P.1223–1239.

Radtke C., Akiyama Y., Brokaw J. et al. Remyelination of the nonhuman primate spinal cord by transplantation of H-transferase transgenic adult pig olfactory ensheathing cells // FASEB J. — 2004. — V.18, N2. — P.335–337.

Raisman G. Olfactory ensheathing cells – another miracle cure for spinal cord injury? // Nat. Rev. Neurosci. — 2001. — V.2, N5. — P.369–374.

Ramer L.M., Richter M.W., Roskams A.J. et al. Peripherally-derived olfactory ensheathing cells do not promote primary afferent regeneration following dorsal root injury // Glia. — 2004. — V.47, N.2. — P.189–206.

Ramon-Cueto A., Avila J. Olfactory ensheathing glia: properties and function // Brain Res. Bull. — 1998. — V.46. — P.175–187.

Ramon-Cueto А., Nieto-Sampedro М. Glial cells from adult rat olfactory bulb: immunocytochemical properties of pure cultures of ensheathing cells // Neuroscience. — 1992. — V.47. — P.213–220.

Ramon-Cueto A., Plant G.W., Avila J., Bunge M.B. Long-distance axonal regeneration in the transected adult rat spinal cord is promoted by olfactory ensheathing glia transplants // J. Neurosci. — 1998. — V.18, N10. — P.3803–3815.

Richter M.W., Fletcher P.A., Liu J. et al. Lamina propria and olfactory bulb ensheathing cells exhibit differential integration and migration and promote differential axon sprouting in the lesioned spinal cord // J. Neurosci. — 2005. — V.25, N46. — P.10700–10711.

Sasaki M., Lankford K.L., Zemedkun M., Kocsis J.D. Identified olfactory ensheathing cells transplanted into the transected dorsal funiculus bridge the lesion and form myelin // J. Neurosci. — 2004. — V.24, N39. — P.8485–8493.

Storan M.J., Magnaldo T., Biol-N'Garagba M.C. et al. Expression and putative role of lactoseries carbohydrates present on NCAM in the rat primary olfactory pathway // J. Comp. Neurol. — 2004. — V.475, N3. — P.289–302.

Takami T., Oudega M., Bates M.L. et al. Schwann cell but not olfactory ensheathing glia transplants improve hindlimb locomotor performance in the moderately contused adult rat thoracic spinal cord // J. Neurosci. — 2002. — V.22, N15. — P.6670–6681.

Woodhall E., West A.K., Chuah M.I. Cultered olfactory ensheathing cells express nerve growth factor, brain-derived neurotrophic factor, glia cell line-derived neurotrophic factor and their receptors // Brain Res. Mol. Brain Res. — 2001. — V.88. — P.203–213.

Zhang X., Klueber K.M., Guo Z. et al. Adult human olfactory neural progenitors cultured in defined medium // Exp. Neurol. — 2004. — V.186, N2. — P.112–123.

How to Cite

Tsymbalyuk, V. I., Semenova, V. M., Yaminsky, Y. Y., & Medvedev, V. V. (2006). Olfactory ensheathing cells potential effectiveness in spinal cord and peripheral nerves injury recovery treatment. Ukrainian Neurosurgical Journal, (4), 4–9. https://doi.org/10.25305/unj.128189

Issue

Section

Review articles