Subtentorial astrocytomas in adults: treatment results


  • Viktor V. Gudkov Romodanov Neurosurgery Institute, Kyiv, Ukraine
  • Liudmyla M. Verbova Romodanov Neurosurgery Institute, Kyiv, Ukraine
  • Volodymyr O. Fedirko Romodanov Neurosurgery Institute, Kyiv, Ukraine
  • Petro M. Onishchenko Romodanov Neurosurgery Institute, Kyiv, Ukraine
  • Tetiana A. Malysheva Romodanov Neurosurgery Institute, Kyiv, Ukraine
  • Oleksandr M. Lisyanyi Romodanov Neurosurgery Institute, Kyiv, Ukraine
  • Oksana G. Chernenko Romodanov Neurosurgery Institute, Kyiv, Ukraine
  • Dmytro M. Tsiurupa Romodanov Neurosurgery Institute, Kyiv, Ukraine



subtentorial astrocytomas, surgical treatment, recurrence disease, morphological characteristics


Objective. To study the clinical and morphological characteristics of subtentorial astrocyte, to prove the recommendations for therapeutic tactics in adults.

Materials and methods. A retrospective analysis was performed on 232 patients with astrocytomas of subtentorial localization (Grade I-IV) undergone the treatment in Romodanov Neurosurgery Institute in the period between 1988 and 2016.

Results. Overall, 20 (8.6%) patients had Grade I astrocytomas, 135(58,2%) – Grade II, 72 (31%) – Grade III and 5 (2.2%) – Grade IV. The main clinical manifestations included: headaches – 94%, coordination disturbances – 89%, nausea/vomiting – 47%. Morphological investigation has been performed. The basic clinical manifestations included headache (94%), disorders in static co-ordination – 89%, nausea and vomiting – 47%. All of the patients were operated. Ninety-seven (41.8%) patients underwent total resection, 51 (22%) – subtotal and 84 (36.2%) – partial. In the most of cases (142 patients), the tumor located in the hemisphere of cerebellum and in the vermis. A microscopic research demonstrated the variety of a histologic structure not only in the different cases, but also in the same tumor. Thirty-six (15.5%) patients were re-operated due to tumor.

Conclusions. Regardless of removed tumors volume, generally the astrocytomas of fossa posterior have favourable prognosis. Nevertheless, they require further investigations, especially Higth Grade III-IV.

Author Biographies

Viktor V. Gudkov, Romodanov Neurosurgery Institute, Kyiv

Subtentorial Neurooncology Department

Liudmyla M. Verbova, Romodanov Neurosurgery Institute, Kyiv

Department of Pediatric Neurosurgery

Volodymyr O. Fedirko, Romodanov Neurosurgery Institute, Kyiv

Subtentorial Neurooncology Department

Petro M. Onishchenko, Romodanov Neurosurgery Institute, Kyiv

Subtentorial Neurooncology Department

Tetiana A. Malysheva, Romodanov Neurosurgery Institute, Kyiv

Neuropathomorphology Department

Oleksandr M. Lisyanyi, Romodanov Neurosurgery Institute, Kyiv

Subtentorial Neurooncology Department

Oksana G. Chernenko, Romodanov Neurosurgery Institute, Kyiv

Neuropathomorphology Department

Dmytro M. Tsiurupa, Romodanov Neurosurgery Institute, Kyiv

Subtentorial Neurooncology Department


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How to Cite

Gudkov, V. V., Verbova, L. M., Fedirko, V. O., Onishchenko, P. M., Malysheva, T. A., Lisyanyi, O. M., Chernenko, O. G., & Tsiurupa, D. M. (2018). Subtentorial astrocytomas in adults: treatment results. Ukrainian Neurosurgical Journal, (1), 41–49.



Original articles