Method choice for craniopharyngiomas treatment

Authors

  • G. M. Kariev Scientific center of neurosurgery of Ministry of Health of Uzbekistan Republic, Tashkent, Uzbekistan
  • N. Kh. Tukhtaev Scientific center of neurosurgery of Ministry of Health of Uzbekistan Republic, Tashkent, Uzbekistan
  • U. U. Altibaev Scientific center of neurosurgery of Ministry of Health of Uzbekistan Republic, Tashkent, Uzbekistan

DOI:

https://doi.org/10.25305/unj.108008

Keywords:

craniopharyngioma, occlusive hydrocephalus, surgical treatment methods, endoscopic third ventriculostomy (ETV), quality of life, Karnofsky Scale

Abstract

Treatment results of 71 patients, operated because of craniopharyngiomas, at whom 95 operations were performed, that has made 1,3 surgical interventions per one patient, were analyzed. Age of patients was from 2 to 63 years. Conducting clinical syndromes depending on age, sizes and an anatomic variant of tumor growth were selected and clinical features of disease were determined. While quality of life estimation according to Karnofsky Scale it was revealed that at punction method application the quality of life after operation increased on 9,6 points, but further decreased on 7 points because of often relapses and necessity of repeated operations performing. At endoscopic method application quality of life after operation increased on 15 points and on 14,1 points more in remote terms. At microsurgical removal of a tumor quality of life after operation increased on 6,7 points and on 10,9 points more — in remote terms. On the basis of obtained data analysis the algorithm for surgical treatment of patients with craniopharyngiomas was developed.

References

Коновалов А.Н., Краснова Т.С., Кадашев Б.А. Микрохирургия краниофарингиом: основные положения и результаты // III Всесоюз. съезд нейрохирургов: Тез. докл. — М., 1982. — С.201–202.

Bunin G.R., Surawicz T.S., Witman P.A. The descriptive epidemiology of craniopharyngioma // J. Neurosurg. — 1998. — V.89. — Р.547–551.

Haupt R., Magnani C., Pavanello M. Epidemiological aspects of craniopharyngioma // J. Pediatr. Endocrinol. Metab. — 2006. — V.19. — Р.289–293.

Karavitaki N., Cudlip S., Adams C.B. Craniopharyngiomas // Endocr Rev. — 2006. — V.27. — Р.371–397.

Karnofsky D.A., Abellmaann W.Y., Craver L.F. The use of the nitrogen mutards in the palliative treatment of carcinoma // Cancer. — 1948. — V.1. — P.634–656.

Kuratsu J., Ushio Y. Epidemiological study of primary intracranial tumours in childhood. A population-based survey inKumamoto// Prefect. Jap. Pediatr. Neurosurg. — 1996. — V.25. — Р.240–246.

Rickert C. H., Paulus W. Lack of chromosomal imbalances in adamantinomatous and papillary craniopharyngiomas // J. Neurol. Neurosurg. Psychiatry. — 2003. — V.74. — Р.260–261.

Published

2009-12-30

How to Cite

Kariev, G. M., Tukhtaev, N. K., & Altibaev, U. U. (2009). Method choice for craniopharyngiomas treatment. Ukrainian Neurosurgical Journal, (4), 30–35. https://doi.org/10.25305/unj.108008

Issue

Section

Original articles