Molecular biomarkers for prognosis and optimal treatment strategy of glioblastomas

Authors

  • L. A. Dzyak Dnepropetrovsk State Medical Academy, Dnepropetrovsk, Ukraine
  • N. A. Zorin Dnepropetrovsk State Medical Academy, Dnepropetrovsk, Ukraine
  • A. G. Sirko Dnepropetrovsk State Medical Academy, Dnepropetrovsk, Ukraine
  • V. I. Shpohnka Dnepropetrovsk State Medical Academy, Dnepropetrovsk, Ukraine
  • A. V. Kozinskiy Dnepropetrovsk State Medical Academy, Dnepropetrovsk, Ukraine

DOI:

https://doi.org/10.25305/unj.107987

Keywords:

глиобластома, иммуногистохимические методы, таргетная терапия, темозоломид, MGMT, EGFR, PTEN

Abstract

An overview of recent publications, dedicated to molecular biomarkers role in prognosis and optimal treatment strategy of glioblastomas, based on targeted therapy approach, is presented. The emphasis is made on those biomarkers that were extensively studied. Also clinical trials data, in which various glioblastoma treatment regimens were studied, are given.

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Published

2009-12-30

How to Cite

Dzyak, L. A., Zorin, N. A., Sirko, A. G., Shpohnka, V. I., & Kozinskiy, A. V. (2009). Molecular biomarkers for prognosis and optimal treatment strategy of glioblastomas. Ukrainian Neurosurgical Journal, (4), 4–8. https://doi.org/10.25305/unj.107987

Issue

Section

Review articles