Pathogenetic approach to the treatment of hormone-dependent brain meningiomas
Keywords:
meningioma brain, hormone, pathogenetic therapy, morphology, medical pathomorphosisAbstract
On the base of 42 brain meningiomas of different histological structure and the degree of malignancy their hormonal dependence has been defined. The structural and metabolic peculiarities of these tumors have been studied. The factors of hormonal dependence of some forms of brain meningiomas have been defined and the expediency of including of pathogenic treatment methods such as hormones (antiestrogens and antiprogestins) have been proved. The per formed catamnestic analysis proved the necessity of administration of hormone medicines after surgical treatment and detailed morphological examination.
References
Бассалык Л.С. Рецепторы стероидных гормонов в опухолях человека. — М.: Медицина, 1987. — 223 с.
Бохман Я.В., Мерабишвили В.М., Семиглазов В.Ф. Патогенетические подходы к профилактике и лечению гормонозависимых опухолей. — Л.:Медицина, 1983. — C.11–22.
Зозуля Ю.А., Кваша М.С. Рецепторы стероидных гормонов, пролиферативная активность и клинико-морфологические особенности менингиом головного мозга //Укр. нейрохірург. журн. — 2002. — №2. — С.81–86.
Козлов А.В. Биология менингиом: современное состояние проблемы // Вопр. нейрохирургии. — 2001. — №1. — С.32–38
Коршунов А.Г., Шишкина Л.В., Голанов А.В. Пролиферативные маркеры в менингиомах: иммуногистохимическое исследование и анализ прогностической значимости // Арх.патол. — 2002. — №1. — С.29–33.
Кушлинский Н.Е. Возможности, неудачи и перспективы исследования опухолевых маркеров //Клин. лаб. диагностика. — 1999. — №3. — С.25–32.
Тиглиев Г.С., Олюшин В.Е., Кондратьев А.Н. Внутричерепные менингиомы. — СПб., 2001. — С.318–345.
Хоминский Б.С. Опухоли нервной системы// Многотомное руководство по патологической анатомии. — М.: Медгиз, 1962. — Т.2. — 560 с.
Brandis A., Mirzai S., Tatagiba M. et al. Immunohistochemical detection of female sex hormone receptors in meningiomas: correlation with clinicaland histological features // Neunsurgery. — 1993. — V. 33. — P.212–217.
Cahill D.W. Estrogen and progesterone receptors in meningiomas // J.Neurosurg.. — 1984. — V.60, N 5. — P.585–593.
Chason J.L. Meningiomas and Their Surgica Management/ Ed.H.H. Schmidek.– Philadelphia, 1991. — P.3–9.
Hinton D. Steroid receptors in meningiomas. A hystohemical and biochemical study//Acta Neurolpathol. — 1983. — V.62, N1–2. — P.134–140.
Hsu D.W, Etird J.T, Hedley Whyte E.T. Progesterone and estrogen receptors in meningiomas: prognostic considerations// J. Neurosurg. — 1997. — V.86. — P.113–120.
Kepes J.J. Meningiomas: Biology, Pathology and Differential Diagnosis. — New York, 1982. — P.38.
Kolles H., Niedermayer I., Schmitt C., Henn W., Fold R., Steudel W.l., Zing K.D., Feiden W. Triple approach for diagnosis and grading of meninfiomas: histology, morphometry of Ki–67 Feulgen stainings, and cytogenetict //Acta neurochir. Wien. — 1995. — V. 137. — P. 174–181.
Kleihues P., Burger P.C., Scheithauer B.W. The new WHO classification of brain tumours //Brain Pathol. — 1993. — N 3. — Р.255–268.
Mairr H., Ofner D., Hittmair A., Kitz K., Budka H. Classic, atypical and anaplastic meningioma: three histopatholi gical subtypes of clinical relevance// J.Neurosurg. — 1992. — V. 77. — P. 616–623.
Matsuno A., Fujimaki T., Sasaki T.,et al. Clinical and histopathological analysis of proliferative potentials of recurrent and non-recurrent meningiomas// Acta Neuropathol. Berl. — 1996. — V.91. — P. 504–510.
Downloads
How to Cite
Issue
Section
License
Copyright (c) 2003 Y. A. Zozulya, M. S. Kvasha, M. I. Shamaev, T. A. Malysheva
This work is licensed under a Creative Commons Attribution 4.0 International License.
Ukrainian Neurosurgical Journal abides by the CREATIVE COMMONS copyright rights and permissions for open access journals.
Authors, who are published in this Journal, agree to the following conditions:
1. The authors reserve the right to authorship of the work and pass the first publication right of this work to the Journal under the terms of Creative Commons Attribution License, which allows others to freely distribute the published research with the obligatory reference to the authors of the original work and the first publication of the work in this Journal.
2. The authors have the right to conclude separate supplement agreements that relate to non-exclusive work distribution in the form of which it has been published by the Journal (for example, to upload the work to the online storage of the Journal or publish it as part of a monograph), provided that the reference to the first publication of the work in this Journal is included.