Using short-term organ culture for the human brain gliomas individual drug sensitivity
Keywords:
glioma, individual sensitivity, H3-thymidineAbstract
Human gliomas have clear expressed individual drug sensitivity. For determination most effective medicine tumor tissue mast be tested. We propose to use for this matter H3—thymidine incorporation test on the short-term cultures. Received results can be used in the clinical practis.
References
Бондарь Г.В., Кайряк О.В., Лисовская Н.Ю. и др. Определение чувствительности к 5-фторурацилу у больных злокачественными опухолями различных локализаций // Антибиотики и химиотерапия. — 1999 — Т.44.— №2. — С.25—29.
Культура животных клеток. Методы/ Под. ред. Р. Фрешни. М.: Мир, 1989. — С. 256—302.
Лихтенштейн А.В., Шапот В.С. Опухолевый рост: ткани, клетки, молекулы // Патофизиология и экспериментальная химиотерапия. — 1998. — №3.— С.25—49.
Противоопухолевая терапия /Под ред. Н.И. Переводчиковой.— М.: Медицина, 1993. —С.121—122.
Abe T., Hasegawa S., Taniguchi K., Yokomizo A., Kuwano T., Ono M., Mori T., Hori S., Kohno K., Kuwano M. Possible involvement of multidrug-resistance-associated protein (MRP) gene expression in spontaneous drug resistance to vincristine, etoposide and adriamycin in human glioma cells// Cancer Res.—1992— V. 52.— N11.— P.3029—3034.
Alvarez M., Robey R., Sandor V., Nishiyama K., Hatsumoto Y., Paull K., Bates S., Fojo T . Using the national cancer institute anticancer drug screen to assess the effect of MRP expression on drug sensitivity profiles // Mol. Pharmacol. — 1998.— V.54.— N5.— P.802—814.
Balmaceda C. Advances in brain tumor chemosensitivity // Tumori. — 1999.— Sep—Oct;83 —. P.17—20
Barranco S.C.,Durm M.E. Direct drug sensitivity test (DDS)// Cell proliferation.—1993.— V.26.— N 4.— P.369.
Jordan J.P., Hand C.M., Markowitz R.S., Black P. Test for chemotherapeutic sensitivity of cerebral gliomas: use of colorimetric MTT assay// J Neurooncol.— 1992.— V.14.— N1.— P.19—35.
Molecula genetics of drug resistens. Ed. by J.D. Hayes and C.R. Wolf.Amsterdam, Harwood Academic Publishers. — V.1997.— 412p.
Petrini M., Galimberti S. Treatment of multidrug resistance in oncology and hematology //Tumori.— 1997.— 83(5 Suppl).— P.17—20.
Schold S.C.,Friedman H.S.,Brent T.P. et al. O6- alkylguanine-DNA alkyltransferase in primary central nervous system neoplasm// J. Neuro-Oncol. —1989.— Suppl.— P.25.
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Copyright (c) 2000 Yuriy Zozulya, Irina Vasileva, Volodymyr Rozumenko, Natalia Olexenko, Oleksandr Glavatskyi, Olga Chuvashova
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