Chemotherapy of meningiomas. Realities and prospects
Keywords:
meningioma, chemotherapy, growth factorsAbstract
Meningioma is one of the popular benign brain tumors. The authors present the evidence that meningiomas respond to chemotherapy in patients with recurrent and unresectable meningiomas. Inhibition of neovascularization is one potential strategy for treating these hypervascular tumors. High levels of growth factors and their receptors have been demonstrated in human tumors. Meningiomas are characterized by overexpression of epidermal growth factor, vascular endothelial growth factor, platelet derived growth factor.
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