The role of neural stem progenitors in the process of emergence and development of some brain tumours and during the epileptogenesis

Authors

  • V. I. Tsymbalyuk Romodanov Neurosurgery Institute, Kiev, Ukraine
  • V. V. Medvedev Romodanov Neurosurgery Institute, Kiev, Ukraine

Keywords:

neuronal stem cell, glial brain tumors, progression of tumors, epileptogenesis, mutations

Abstract

On the graunds of scientific data the article highlights the issues of some brain tumours’ genealogy and participation of neural stem cells (NSC) in the processes of oncogenic transformation and tumour progression. The authors consider the role of NSC in epileptogenesis and possible mechanisms of mutation transformation of NSC.

References

Гайкова О.Н., Новожилова А.П. Морфология эпилептической лейкоэнцефалопатии // Арх. патологии. — 1998. — Т.60, №2. — С.42–47.

Крыжановский Г.Н., Магаева С.В., Макаров С.В. Нейроиммунопатология. — М.: Ин-т общ. патологии и патофизиологии РАМН, 1997. — 282 с.

Руденко В.А., Маркова О.В. Иммунные свойства клеток головного мозга // Иммунная система головного мозга. — К.: ВИПОЛ, 1999. — С.32–49.

Aboody K.S., Brown A., Rainov N.G. et al. Neural stem cells display extensive tropism for pathology in adult brain: evidence from intracranial gliomas // PNAS USA. — 2000. — V.97, N23. — P.12846–12851.

Alvarez-Buylla A., Garcia-Verdugo J.M., Tramontin A.D. A unified hypothesis on the lineage of neural stem cells // Nat. Rev. Neurosci. — 2001. — V.2, N4. — P.287–293.

Bachoo R.M., Maher E.A., Ligon K.L et al. Epidermal growth factor receptor and Ink4a/Arf: convergent mechanisms governing terminal differentiation and transformation along the neural stem cell to astrocyte axis // Cancer Cell. — 2002. — V.1, N3. — P.296–277.

Baudino T.A., McKay C., Pendeville-Samain H. et al. c-Myc is essential for vasculogenesis and angiogenesis during development and tumor progression // Gen. Dev. — 2002. — V.16, N19. — P.2530–2543.

Benedetti S., Pirola B., Pollo B et al. Gene therapy of experimental brain tumors using neural progenitor cells // Nat. Med. — 2000. — V.6, N4. — P.369–370.

Berkman R.A., Merrill M.J., Reinhold W.C. et al. Expression of the vascular permeability factor/vascular endothelial growth factor gene in central nervous system neoplasms // J. Clin. Invest. — 1993. — V.91, N1. — P.153–159.

Bjorklund A., Svedsen C. Breaking the brain-blood barrier // Nature. — 1999. — V.397, N6720. — P.569–570.

Bjornson C.R.R., Rietze R.L., Reynolds B.A et al.. Turning brain into blood : a hematopoietic fate adapted by adult stem cells in vivo // Science. — 1999. — V.283, N5401. — P.534–566.

Blumcke I., Schewe J.C., Normann S. et al. Increase of nestin-immunoreactive neural precursor cells in the dentate gyrus of pediatric patients with early-onset temporal lobe epilepsy // Hippocampus. — 2001. — V.11, N3. — P.311–321.

Buhren J., Christoph A.H., Buslei R. et al. Expression of the neurotrophin receptor p75NTR in medulloblastomas is correlated with distinct histological and clinical features: evidence for a medulloblastoma subtype derived from the external granule cell layer // J. Neuropathol. Exp. Neurol. — 2000. — V.59, N3. — P.229–240.

Cecconi F., Alvarez-Bolado G., Meyer B.I. et al. Apafl (CED-4 homolog) regulates programmed cell death in mammalian development // Cell. — 1998. — V.94, N6. — P.727–737.

Darhell R.B. Immunologic complexity in neurons // Neuron. — 1998. — V.21, N5. — P.947–950.

Dirks P.B. Glioma migration: clues from the biology of neural progenitor cells and embryonic CNS cell migration // J. Neurooncol. — 2001. — V.53, N2. — P.203–212.

Duggal N., Hammond R.R. Nestin expression in ganglioglioma // Exp. Neurol. — 2002. — V.174, N1. — P.89–95.

Ekdahl C.T., Mohapel P., Weber E. et al. Caspase-mediated death of newly formed neurons in the adult rat dentate gyrus following status epilepticus // Europ. J. Neurosci. — 2002. — V.16, N8. — P.1463–1471.

Ferland R.J., Gross R.A., Applegate C.D. Increased mitotic activity in the dentate gyrus of the hippocampus of adult C57BL/6J mice exposed to the flurothyl kindling model of epileptogenesis // Neuroscience. — 2002. — V.115, N3. — P.669–683.

Fuchs E., Segre J.A. Stem cells: a new lease on life // Cell. — 2000. — V.100, N1. — P.143–155.

Fukunaga A., Uchida K., Hara K. et al. Differentiation and angiogenesis of central nervous system stem cells implanted with mesenchyme into ischemic rat brain // Cell. Transplant.— 1999. — V.8, N4. — P.435–441.

Gage F.H. Mammalian neural stem cells // Science. — 2000. — V.287, N5451. — P.1433–1438.

Gould E., Vail N., Wagers M., Gross C.G. Adult generated hippocampal and neocortical neurons in macaques have a transient existence // PNAS USA. — 2001. — V.98, N19. — P.10910–10917.

Hashimoto T., Mesa-Tejada R., Quick C.M. et al. Evidence of increased endothelial cell turnover in brain arteriovenous malformations // Neurosurgery. — 2001. — V.49, N1. — P.124–131.

Hattori K., Heissig B., Wu Y. et al. Placental growth factor reconstitutes hematopoiesis by recruiting VEGFR1(+) stem cells from bone-marrow microenvironment // Nat. Med. — 2002. — V.8, N8. — P.841–849.

Hodozuka A., Hashizume K., Nakai H., Tanaka T. Vascular abnormalities in surgical specimens obtained from the resected focus of intractable epilepsy // Brain Tumor Pathol. — 2000. — V.17, N3. — P.121–131.

Ignatova T.N., Kukekov V.G., Laywell E.D. et al. Human cortical glial tumors contain neural stem-like cells expressing astroglial and neuronal markers in vitro // Glia. — 2002. — V.39, N3. — P.193–206.

Konopka G., Bonni A. Signaling pathways regulating gliomagenesis // Curr. Mol. Med. — 2003. — V.3, N1. — P.73–84.

Lawn N., Londono A., Sawrie S. et al. Occipitoparietal epilepsy, hippocampal atrophy, and congenital developmental abnormalities // Epilepsia. — 2000. — V.41, N12. — P.1546–1553.

Leonard J.R., D’Sa C., Klocke B.J., Roth K.A. Neural precursor cell apoptosis and glial tumorigenesis following transplacental ethyl-nitrosourea exposure // Oncogene. — 2001. — V.20, N57. — P.8281–8286.

Malatesta P., Hartfuss E., Gotz M. Isolation of radial glial cells by fluorescent-activated cell sorting reveals a neuronal lineage // Development. — 2000. — V.127, N24. — P.5253–5263.

Maurer M.H., Tripps W.K., Feldmann R.E.Jr., Kuschinsky W. Expression of vascular endothelial growth factor and its receptors in rat neural stem cells // Neurosci. Lett. — 2003. —V.344, N3. — P.165–168.

Modo M., Mellodew K., Rezaie P. In vitro expression of major histocompatibility class I and class II antigenes by conditionally immortalized murine neural stem cells // Neurosci. Lett. — 2003. — V.337, N2. — P.85–88.

Nakagawa E., Aimi Y., Yasuhara O et al. Enhancement of progenitor cell division in the dentate gyrus triggered by initial limbic seizures in rat models of epilepsy // Epilepsia. — 2000. —V. 41, N1. — P.10–18.

Noctor S.C., Flint A.C., Weissmann T.A. et al. Neurons derived from radial glial cells establish radial units in neocortex // Nature. — 2001. — V.409, N6821. — P.714–720.

Onda H., Crino P.B., Zhang H. et al. Tsc2 null murine neuroepithelial cells are a model for human tuber giant cells, and show activation of an mTOR pathway // Mol. Cell. Neurosci. — 2002. — V.21, N4. — P.561–574.

Parati E.A., Bez A., Ponti D. et al. Human neural stem cells express extra-neural markers // Brain Res. — 2002. — V.925, N2. — P.213–221.

Parent J.M., Lowenstein D.H. Seizure-induced neurogenesis: are more new neurons good for an adult brain? // Prog. Brain Res. –2002. —V.135. — P.121–31.

Praag H., Kempermann G.,Cage F.H. Running increases cell proliferation and neurogenesis in the adult mouse dentate gyrus // Nat. Neurosci. — 1999. — V2. — P.266–70.

Recht L., Jang T., Savarese T., Litofsky N.S. Neural stem cells and neuro-oncology: quo vadis? // J. Cell Biochem. — 2003. — V.88, N. — P.11–19.

Rehen S.C., McConnell M.I., Kaushal D. et al. Chromosomal variation in neurons of the developing and adult mammalian nervous system // PNAS USA. — 2001. — V.98, N23. — P.13361–13366.

Rutherford S.L., Lindquist S. Hsp90 as a capacitor for morphological evolution // Nature. — 1998. - V.396, N6709. — P.336–342.

Sato K., Iwai M., Nagano I. et al. Temporal and spacial changes of BrdU immunoreactivity in amygdala kindling development // Neurol. Res. — 2002.— Vol.24, N6. — P.593–596.

Sato K., Iwai M., Nagano I., Shoji M., Abe K. Temporal and spacial changes of highly polysialylated neural cell adhesion molecule immunoreactivity in amygdala kindling development // Neurol. Res. — 2003. — V.25, N1. — P.79–82.

Scharfman H.E., Goodman J.H., Sollas A.L. Granule-like neurons at the hilar/CA3 border after status epilepticus and their synchrony with area CA3 pyramidal cells: functional implications of seizure-induced neurogenesis // J. Neurosci. — 2000. — V.20, N16. — P.6144–6158.

Scheffler B., Horn M., Blumcke I. et al. Marrow-mindedness : a perspective on neuropoiesis // TINS. — 1999. — V.22, N8. — P.348–357.

Shors T.J., Miesegaes G., Beylin A. et al. Neurogenesis in the adult is involved in the formation of trace memories // Nature. — 2001. — V.410, N6826. — P.372–375.

Syken J., Shatz C.J. Expression of T- cell receptor beta locus in central nervous system neurons // PNAS USA. — 2003. — V.100, N22. — P.13048–13053.

Temple S. The development of neural stem cells // Nature. — 2001. — V.414, 6859. — P.112–117.

Uhrbom L., Dai C., Celestino J.C. et al. Ink4a-Arf loss cooperates with KRas activation in astrocytes and neural progenitors to generate glioblastomas of various morphologies depending on activated Akt // Cancer Res. — 2002. — V.62, N19. — P.5551–5558.

How to Cite

Tsymbalyuk, V. I., & Medvedev, V. V. The role of neural stem progenitors in the process of emergence and development of some brain tumours and during the epileptogenesis. Ukrainian Neurosurgical Journal, (1), 9–14. Retrieved from https://theunj.org/article/view/137781

Issue

Section

Review articles