DOI: https://doi.org/10.25305/unj.134714

Cerebrospinal fluid flow. Part 1. Classical theory and its evolution

Ievgenii I. Slynko, Alexey S. Nekhlopochin

Abstract


Cerebrospinal fluid plays a huge physiological role in the normal functioning of the human CNS. Its changes serve as a kind of indicator of a significant number of pathological processes. However, despite such importance, the analysis of the literature demonstrates rather a small number of works devoted to a detailed description of the mechanisms of cerebral fluid flow. In the era of significant development of experimental techniques, the use of electron microscopy, radioisotope and immunological methods, many aspects of cerebrospinal fluid flow remain unexplored. The presented review is an attempt to order the available data and to reflect the evolution of ideas about cerebrospinal fluid flow in the historical aspect, relying on known publications.


Keywords


cerebrospinal fluid; cerebrospinal fluid flow; classical theory; evolution

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