The characteristic of cell immunity indexes in different brain tumors
Keywords:
імунітет, гліома, менінгіома, метастатичні пухлини.Abstract
The different lymphocytic subpopulations (T-, B-cells, helpers, cytotoxic lymphpocytes, natural killers, apoptotic and activated lymphocytes) were examined in patients with glioma, meningioma and metastatic tumor. It was determined, that each tumor has its own specific cell immune peculiarities. Glioma have the great influense on the different lymphocytic subsets.
References
1. Дранник Г.Н. Клиническая иммунология и аллергология: Учебное пособие. — Одесса : Астропринт, 1998. — 604 с.
2. Зозуля Ю.П., Лісяний М.І. Нейрогенний імунодефіцит при вогнищевих ураженнях головного мозку та його клінічне значення // Журн. АМН України. — 1998. — Т.4, №1. — C.44—63
3. Ковальчук Л.В., Чередеев А.Н. Апоптогенные механизмы возникновения иммунодефицитных заболеваний // Журн. микробиологии, эпидемиологии и иммунологии. — 1999. — №5. — С.47—52
4. Лисяный Н.И., Мамытов М.М. Изменение иммунологических показателей у больных с опухолями головного мозга // Вопр. нейрохирургии. — 1985. — №6. — C.43—46.
5. Малашхия Ю.А., Ломджария Л.Д., Сигуа О.А. Некоторые показатели состояния Т- и В-систем иммунитета при опухолях головного мозга // Иммунология. — 1981. — №2. — С.36—39
6. Сидоренко С.П. Поверхностные антигены клеток человека, систематизированные международными рабочими совещаниями по дифференцировочным антигенам лейкоцитов человека // Імунологія та алергологія. — 1998. — №3. — С.16—38.
7. Шепелева И.И., Чехонин В.П. Нейрональные молекулы клеточной адгезии (структура, функции, клинико-диагностические перспективы) // Журн. неврологии и психиатрии им. С.С.Корсакова. — 1996. — №5. — С.113—118
8. Ashkenazi E., Deutsch M., Tirosh R. et al. A selective impairment of the IL-2 system in lymphocytes of patients with glioblastomas: increased level of soluble IL-2 R and redused protein tyrosine phosphоrilation // Neuroimmunomodulation. — 1997. — V.4, N 1. — P.49—56.
9. Bently G.A., Mariuzza R.A. The structure of the T-cell antigen receptor// Ann. Rev. Immunology. — 1996. — V.15. — P.563—590.
10. Lenartz D., Stoffel B., Mensel J. et al. Immunoprotective activity of the galactoside-specific lectin from mistletoe after tumor destructive therapy in glioma patients // Anticancer Res. — 1996. — V. 16, N 6. — P. 3799—3802.
11. Matsushisa T. Subset analysis of tumor infiltrating lymphocytes and peripheral blood lymphocytes in malignant glioma patients // Brain and Nerve. — 1995. — V. 45, N 5. — P.466—473.
12. Morford L.A., Elliot Lh., Carlson S.L. et al. T‑cell receptor signaling is defective in T-cells obtained from patients with primary intracranial tumors // J. Immunol. — 1997. — V.159, N 9. — P. 4415—4425.
13. Parney I.F., Farr-Jones M.A., Chang L.J. Human glioma immunobiology in vitro: implications for immunogene therapy // Neurosurgery. — 2000. — V.46, N 5. — P.1169—1177.
14. Weller M., Fontana A. The failure of current immunotherapy for malignant glioma. Tumor-derived TGF beta, T—cell apoptosis and the immune privilege of the brain// Brain Res. — 1995. — V.21, N 2. — P.128—151.
15. Zipp F., Martin R., Lichtenfels R. et al. Human autoreactive and foreign-specific T-cell resist apoptosis induced by soluble recombinant CD95 ligand // J. Immunol. — 1997. — V.159, N 5. — P.2108—2115.
16. Zou J.P., Morford L.A., Chougnet C. et al. Apoptotic elimination of peripheral T-lymphocytes in patients with primary intracranial tumors // J. Neurosurg. — 1999. — V.162. — P. 935—946.
Downloads
How to Cite
Issue
Section
License
Copyright (c) 2002 S. A. Skityak
This work is licensed under a Creative Commons Attribution 4.0 International License.
Ukrainian Neurosurgical Journal abides by the CREATIVE COMMONS copyright rights and permissions for open access journals.
Authors, who are published in this Journal, agree to the following conditions:
1. The authors reserve the right to authorship of the work and pass the first publication right of this work to the Journal under the terms of Creative Commons Attribution License, which allows others to freely distribute the published research with the obligatory reference to the authors of the original work and the first publication of the work in this Journal.
2. The authors have the right to conclude separate supplement agreements that relate to non-exclusive work distribution in the form of which it has been published by the Journal (for example, to upload the work to the online storage of the Journal or publish it as part of a monograph), provided that the reference to the first publication of the work in this Journal is included.
