Qualitу of life at children with critical hydrocephalus

Authors

  • Yuriy Orlov Romodanov Neurosurgery Institute, Kiev, Ukraine
  • Igor Malovichko Romodanov Neurosurgery Institute, Kiev, Ukraine
  • Leonid Marushchenko Romodanov Neurosurgery Institute, Kiev, Ukraine https://orcid.org/0000-0001-9020-5402
  • Anna Shmeleva Romodanov Neurosurgery Institute, Kiev, Ukraine

DOI:

https://doi.org/10.25305/unj.59040

Keywords:

critical hydrocephalus, ventriculoperitoneal shunt operations, results of treatment, children

Abstract

Introduction. In article modern views at a problem of treatment of critical hydrocephalus at children were analysed.

Materials and methods. The purpose of research was to study the results of shunt operations of 96 children with critical hydrocephalus. Age of patients was from three months to two years. Ventriculoperitoneostomy was performed in all children. Histological research of biopsy materials of cerebral tissue were conducted in 10 cases. A catamnesis was followed for 2–17 years.

Results. In 49% cases after operation good (in 19%) or satisfactory (in 30%) quality of patients’ life was achieved. At microscopic research of brain tissue the correlation of destructive changes rate and hydrocephalus severity, caused not only by hypertension, was established.

Conclusions. At critical hydrocephalus changes in brain tissue mostly concern damage of glial cells. Maintenance of considerable part of neurons and glial cells proliferation are important pre-condition for neural cells reparation and cerebral functions renewing. Inflammatory and vascular etiology of hydrocephalus have negative influence.

Author Biographies

Yuriy Orlov, Romodanov Neurosurgery Institute, Kiev

Pediatric Neurosurgery Department

Igor Malovichko, Romodanov Neurosurgery Institute, Kiev

Pediatric Neurosurgery Department

Leonid Marushchenko, Romodanov Neurosurgery Institute, Kiev

Pediatric Neurosurgery Department

Anna Shmeleva, Romodanov Neurosurgery Institute, Kiev

Neuropathomorphological Department

References

1. Faghih Jouibari M, Baradaran N, Shams Amiri R, Nejat F, El Khashab M. Huge hydrocephalus: definition, management, and complications. Childs Nerv Syst. 2010;27(1):95-100. [PubMed]

2. Zinenko D. [Clinico-pathogenetic characteristic of post-hemorrhagic hydrocephalus, optimize its diagnosis and treatment of premature infants] [dissertation]. Moscow (Russia): Burdenko Neurosurgery Institute; 2010. Russian.

3. Orlov Y, Marushchenko L, Protsenko I. [Results of hydrocephalus surgical treatment caused by perinatal brain injury at children]. Ukrainian Neurosurgical Journal. 2009;(2):75–79.Ukrainian.

4. Orlov Y, Protsenko I, Marushchenko L. Yakist zhyttya ditey z hidrotsefaliyeyu, operovanykh v hrudnomu vitsi [The quality of life of children with hydrocephalus operated in infancy]. Sotsialnaya pediatriya i reabilitolohiya. 2007;1(4):84–89. Ukrainian.

5. Drake J. The surgical management of pediatric hydrocephalus. Neurosurgery. 2008;62(Supplement 2):633-640. [CrossRef] [PubMed]

6. Drake J. The surgical management of pediatric hydrocephalus. Neurosurgery. 2008;62(Supplement 2):633-640. [CrossRef] [PubMed]

7. Orlov Y. [An estimation of quality of life of the patients with defeats of the central nervous system]. Ukrainian Neurosurgical Journal. 2001;(1):89–94. Russian. [Abstract/Full Text]

8. Chazal J. Management of hydrocephalus in childhood. In: Practical Handbook of Neurosurgery. Springer Vienna, 2009. p.1025-1041.

9. Sgouros S, Kulkharni A, Constantini S. The international infant hydrocephalus study: concept and rational. Childs Nerv Syst. 2006;22(4):338-345. [CrossRef] [PubMed]

10. Rosin Y. Dopplerografiya Sosudov Golovnogo Mozga U Detey [Doppler Blood Vessels Of The Brain In Childrens]. St. Peterburg: Izdatel'skii dom SPbMAPO; 2006. Russian.

11. Kharchenko L, Protsenko I, Malovichko I. Narusheniya mozgovogo krovoobrashcheniya u novorozhdennykh kak prichina razvitiya gidrotsefalii (analiticheskiy obzor) [Cerebrovascular accident in infants as a cause of hydrocephalus (Analytical Review)]. Neyrokhirurgiya i nevrologiya detskogo vozrasta. 2008;(1-2):116–122. Russian.

12. Kulkarni A. Quality of life in childhood hydrocephalus: a review. Childs Nerv Syst. 2010;26(6):737-743. [CrossRef] [PubMed]

13. Owens R. Intraventricular Hemorrhage in the Premature Neonate. Neonatal Network: The Journal of Neonatal Nursing. 2005;24(3):55-71. [CrossRef] [PubMed]

14. Futagi Y, Suzuki Y, Toribe Y, Nakano H, Morimoto K. Neurodevelopmental Outcome in Children With Posthemorrhagic Hydrocephalus. Pediatric Neurology. 2005;33(1):26-32. [CrossRef] [PubMed]

Published

2012-06-26

How to Cite

Orlov, Y., Malovichko, I., Marushchenko, L., & Shmeleva, A. (2012). Qualitу of life at children with critical hydrocephalus. Ukrainian Neurosurgical Journal, (2), 8–12. https://doi.org/10.25305/unj.59040

Issue

Section

Original articles