Comparative study of vascular endothelial growth factor receptor-2 expression in spinal tumors

Authors

  • Yuriy Zozulya Romodanov Neurosurgery Institute, Kiev, Ukraine https://orcid.org/0000-0002-0573-2740
  • Irina Vasileva Romodanov Neurosurgery Institute, Kiev, Ukraine
  • Eugene Slynko Romodanov Neurosurgery Institute, Kiev, Ukraine
  • Nataliya Chopik Romodanov Neurosurgery Institute, Kiev, Ukraine

Keywords:

vascular endothelial growth factor, spinal tumors, vascular malformations

Abstract

The vascular endothelial growth factor receptor-2 (KDR) expression in various tumors and vascular malformations of spinal cord was investigated.

The KDR mRNA was detected in all tumor tissues examined. However, we found different degree of VEGF receptor-2 expression in various tumor tissue samples. The highest expression was observed in the metastatic tumors and schwannomas. The KDR expression in vascular tumour and malformation was less pronounced. The meningiomas fall in category of tumour with small expression of VEGF receptor-2 (KDR).

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How to Cite

Zozulya, Y., Vasileva, I., Slynko, E., & Chopik, N. Comparative study of vascular endothelial growth factor receptor-2 expression in spinal tumors. Ukrainian Neurosurgical Journal, (3), 85–92. Retrieved from https://theunj.org/article/view/56211

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