The change of concentration of D-Dimers in disorders of haemostasis at patients with cranio-cerebral trauma

Authors

  • Oleksandr Potapov Jr Sumy State University, Sumy, Ukraine

Keywords:

traumatic brain injury, hemostasis, fibrin degradation products, D-dimers

Abstract

Analized the results of investigations of D-Dimers (D-D) in blood from 74 patients with cranio-cerebral trauma and 15 healthy men by automatized method ЕLFА (VIDAS D-Dimer, bioMeriex). At patients with hard cranio-cerebral trauma was noticed that concentration of D-Dimers increased. High concentration of D-Dimers had place at 32% of patients with hard cranio-cerebral trauma and on 17—19 days after trauma. The founding of D-D is recomended in DIС-syndrome and for control during therapy by heparine.

References

Bach-Gansmo E.T. et al. D-dimers are degraded by human neutrophil elastase// Thromb.Res.— 1996.—N. 82.—Р.177.

Bottasso B. et al. Hypercoagulability and hyperfibrinolysis in patients with melanoma// Thromb.Res.— 1996.—N. 81.—Р. 345.

Breton E. et al. Comparative study of four new and rapid D-Dimer assays to excude deep vien thrombosis or pulmonary embolism// Abstract, XVth Congress of ISTH.— (June, 11—16, 1995). —Jerusalem, 1995.

Comeglio P. еt al. Blood clotting activation during normal pregnancy// Thromb.Res.— 1996.—N 84.—Р.199.

Confrancesco E. et al. Coagulation activation markers in the prediction of venous thrombosis after elective hip surgery// Thromb.Haemost.— 1997.—N.77.—Р. 267.

Dale S. et af. Comparison of three D-Dimer assays for the diagnosis of deep vien thrombosis: ELISA, latex and immunofiltration assay// Thromb. Haemost.— 1994.—N.71.— Р. 270.

Edwin J. et al. The role plasma D-dimer concentration in the exclusion of pulmonary embolism// Br.J.Haematol.—1996.—N.92.—Р. 725.

Gadducci A. et al. Preoperative evaluation of D-dimer and CA 125 levels in differentiation bening from malignant ovarian masses// Gynecol.Oncol.— 1996.—N.60.—Р.197.

Harvey R.L. et al. Deep vien thrombosis in stroke. The use of plasma D-dimer level as a screening test in the rehabilitation setting// Stroke.— 1996.—N. 27.—Р.1516.

Janssen M.C. et al. D-dimer determination to assess regression of deep venous thrombosis// Thromb.Haemost.— 1997.—N. 78.—Р. 799.

Kopeikina L.T. et al. Imbalance of tissue-type plasminogen activator (t-PA) and its specific inhibitor (PAI-1) in patients with rheumatoid arthritis associated with disease activity// Clin.Rheumatol.— 1977.—N.32.—Р.193.

Kozman H. еt al.Deep venous thrombosis i prediction by D-dimer//South.Med.J.—1997.—N.90.—Р.907.

Perrier et al. D-dimer testing for suspected pulmonary embolism in outpatients// Am. J. Respir. Critcare Med.— 1997.—N.156.—Р. 492.

Reber G. еt al. Comparison of two rapid D-Dimer tests (SimpliRed and VIDAS D-D) to rule out venous thromboembolism// Abstract, XVth Congress of ISTH. (June, 11—16, 1995).— Jerusalem, 1995.

Seitz R. et al. D-dimer test defect both plasmin and neutrophil elastase derived split products// Ann.Clin.Biochem.— 1995.—N. 32.—Р.193.

Taguchi 0. et al. Prognostic significance of plasma D-dimer levels in patients with lung cancer// Thorax.— 1997.—N.52.—Р.563.

Vukovich T.C. et al. Hemostasis activation in patients undergoing brain tumor surgery// J.Neurosurg.— 1997.—N.87.—Р.508.

How to Cite

Potapov Jr, O. The change of concentration of D-Dimers in disorders of haemostasis at patients with cranio-cerebral trauma. Ukrainian Neurosurgical Journal, (3), 62–64. Retrieved from https://theunj.org/article/view/56203

Issue

Section

Original articles