Molecular biomarkers for prognosis and optimal treatment strategy of glioblastomas

L. A. Dzyak, N. A. Zorin, A. G. Sirko, V. I. Shpohnka, A. V. Kozinskiy


An overview of recent publications, dedicated to molecular biomarkers role in prognosis and optimal treatment strategy of glioblastomas, based on targeted therapy approach, is presented. The emphasis is made on those biomarkers that were extensively studied. Also clinical trials data, in which various glioblastoma treatment regimens were studied, are given.


глиобластома; иммуногистохимические методы; таргетная терапия; темозоломид; MGMT; EGFR; PTEN


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