Intraventricular hemorrhage and its fibrinolytic treatment: literature review

Yuris L. Dzenis, Karlis Y. Stirans

Abstract


The review is dedicated to intraventricular hemorrhage (IVH) and its treatment with topical intraventricular fibrinolysis (IVF). We evaluated many clinical factors typical  for  IVH: etiology, classifications, symptoms, diagnostics, qualitative and quantitative  results and in case of re-bleeding the breakdown site where blood enters venricular system.

The paper considers main elements of IVF evaluated, namely indications, external ventricular drain (EVD) techniques, fibrinolytic administration through the drainage catheter vs  intratecali, fibrinolytic dosage used (urokinase, tissue plasminogen activator).

The paper describes the results following IVH: mortality, main complications (re-bleeding, ventriculitis, shunt-dependence ect) and functional outcome. This article reviews the general points associated with IVH and its treatment with topical IVF.


Keywords


intraventricular hemorrhage; fibrinolytics; intraventricular fibrinolysis; occlusive hydrocephalus; external ventricular drainage

References


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DOI: https://doi.org/10.25305/unj.104497

Copyright (c) 2017 Yuris L. Dzenis, Karlis Y. Stirans

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